PMID- 7779007
OWN - NLM
STAT- MEDLINE
DCOM- 19950712
LR  - 20190830
IS  - 0160-564X (Print)
IS  - 0160-564X (Linking)
VI  - 19
IP  - 3
DP  - 1995 Mar
TI  - Present trends in clinical experience with dynamic cardiomyoplasty.
PG  - 211-6
AB  - Dynamic cardiomyoplasty has been performed to reinforce the myocardium in the 
      treatment of patients with severe cardiomyopathies. At the Heart Institute of Sao 
      Paulo University Medical School, 36 patients were submitted to cardiomyoplasty 
      between May 1988 and December 1993. The indications were idiopathic dilated 
      cardiomyopathy in 31, ischemic cardiomyopathy in 3, and Chagas' disease 
      cardiomyopathy in 2 patients. Twenty-eight patients were categorized in New York 
      Heart Association (NYHA) Class III and 8 in Class IV despite the use of maximal 
      medical therapy. There were no hospital deaths, and patients were followed up 
      from 2 to 70 months (mean, 24 months). Besides the improvement of NYHA functional 
      class from 3.2 +/- 0.6 to 1.6 +/- 0.9 at 6 months of follow-up, patients also 
      presented significant changes in the left ventricular systolic and diastolic 
      functions. Nevertheless, 16 patients died, and 2 patients were submitted to heart 
      transplantation during late follow-up. Actuarial survival rates were 82.3% at 1 
      year, 61.5% at 2 years, and 38.8% at 5 years of follow-up. Otherwise, the 
      analysis of factors influencing the outcome showed that long-term survival was 
      significantly affected by preoperative functional class and by pulmonary vascular 
      resistance. The 26 patients operated in NYHA functional Class III and with 
      pulmonary vascular resistance below 4 Wood units presented survival rates of 
      72.7% at 2 years and of 63% at 5 years of follow-up. In conclusion dynamic 
      cardiomyoplasty improves functional class and left ventricular function in 
      patients with severe cardiomyopathies. However, the long-term survival after this 
      surgical procedure may be limited by the patients' condition before the 
      operation.
FAU - Moreira, L F
AU  - Moreira LF
AD  - Heart Institute of Sao Paulo, University Medical School, Brazil.
FAU - Bocchi, E A
AU  - Bocchi EA
FAU - Bacal, F
AU  - Bacal F
FAU - Stolf, N A
AU  - Stolf NA
FAU - Bellotti, G
AU  - Bellotti G
FAU - Jatene, A D
AU  - Jatene AD
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Artif Organs
JT  - Artificial organs
JID - 7802778
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cardiomyopathies/complications
MH  - *Cardiomyoplasty
MH  - Female
MH  - Heart Failure/etiology/mortality/surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Quality of Life
MH  - Survival Rate
MH  - Ventricular Function, Left
EDAT- 1995/03/01 00:00
MHDA- 1995/03/01 00:01
CRDT- 1995/03/01 00:00
PHST- 1995/03/01 00:00 [pubmed]
PHST- 1995/03/01 00:01 [medline]
PHST- 1995/03/01 00:00 [entrez]
AID - 10.1111/j.1525-1594.1995.tb02315.x [doi]
PST - ppublish
SO  - Artif Organs. 1995 Mar;19(3):211-6. doi: 10.1111/j.1525-1594.1995.tb02315.x.