PMID- 7784387
OWN - NLM
STAT- MEDLINE
DCOM- 19950714
LR  - 20190904
IS  - 0197-3851 (Print)
IS  - 0197-3851 (Linking)
VI  - 15
IP  - 3
DP  - 1995 Mar
TI  - Fetal translocation between chromosomes 2, 18, and 21 resolved by fish.
PG  - 278-81
AB  - An apparently balanced t(2q;21q) translocation was discovered in fetal blood and 
      amniocytes of a 22-week fetus, monitored because of ultrasonographic evidence of 
      a heart disease. FISH (fluorescence in situ hybridization) analysis disclosed a 
      complex translocation between chromosomes 2q, 18q, and 21q, which was inherited 
      from the healthy mother. This observation corroborates the usefulness of 
      molecular cytogenetic techniques in raising the quality of prenatal diagnosis and 
      detecting subtle rearrangements not resolved by standard cytogenetics.
FAU - Delaroche, I
AU  - Delaroche I
AD  - Laboratorio Centrale CRI, Roma, Italy.
FAU - Sabani, M
AU  - Sabani M
FAU - Calabrese, G
AU  - Calabrese G
FAU - Mingarelli, R
AU  - Mingarelli R
FAU - Palka, G
AU  - Palka G
FAU - Dallapiccola, B
AU  - Dallapiccola B
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Prenat Diagn
JT  - Prenatal diagnosis
JID - 8106540
SB  - IM
MH  - Adult
MH  - *Chromosomes, Human, Pair 18
MH  - *Chromosomes, Human, Pair 2
MH  - *Chromosomes, Human, Pair 21
MH  - Female
MH  - Heart Defects, Congenital/diagnostic imaging/genetics
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Pregnancy
MH  - *Prenatal Diagnosis
MH  - *Translocation, Genetic
MH  - Ultrasonography, Prenatal
EDAT- 1995/03/01 00:00
MHDA- 1995/03/01 00:01
CRDT- 1995/03/01 00:00
PHST- 1995/03/01 00:00 [pubmed]
PHST- 1995/03/01 00:01 [medline]
PHST- 1995/03/01 00:00 [entrez]
AID - 10.1002/pd.1970150312 [doi]
PST - ppublish
SO  - Prenat Diagn. 1995 Mar;15(3):278-81. doi: 10.1002/pd.1970150312.