PMID- 7785674
OWN - NLM
STAT- MEDLINE
DCOM- 19950719
LR  - 20221207
IS  - 0002-9262 (Print)
IS  - 0002-9262 (Linking)
VI  - 142
IP  - 1
DP  - 1995 Jul 1
TI  - Relation of body fat distribution to ischemic heart disease. The National Health 
      and Nutrition Examination Survey I (NHANES I) Epidemiologic Follow-up Study.
PG  - 53-63
AB  - Although an excess of adipose tissue in the abdominal and truncal regions is 
      associated with various metabolic alterations, relatively few cohort studies have 
      examined its importance in the development of ischemic heart disease, and little 
      information is available from black populations. The authors examined the 
      relation of central obesity, as characterized by a thick subscapular skinfold 
      relative to the triceps skinfold, to the incidence of ischemic heart disease 
      among 9,822 persons in the Epidemiologic Follow-up Study of the National Health 
      and Nutrition Examination Survey I; baseline data were collected in 1971-1975 and 
      follow-up was through 1987. We found that, independently of relative weight, 
      cigarette smoking, and other covariates, the hazard rate ratios for ischemic 
      heart disease incidence contrasting the upper and lower quintiles of central 
      obesity were 1.75 (95% confidence interval 1.3-2.3) among women and 1.65 (95% 
      confidence interval 1.3-2.2) among men. Although central obesity was related 
      similarly to disease among white and black men, the association among women 
      differed between whites (rate ratio = 1.94) and blacks (rate ratio = 0.73); p = 
      0.002 for race x the central obesity product term. Additional research is needed 
      to clarify the relation of various anthropometric measurements to ischemic heart 
      disease, particularly among blacks, but the assessment of fat distribution may 
      help identify high-risk persons for whom weight loss might be most beneficial.
FAU - Freedman, D S
AU  - Freedman DS
AD  - National Center for Chronic Disease Prevention and Health Promotion, Centers for 
      Disease Control and Prevention, Atlanta, GA 30341-3724, USA.
FAU - Williamson, D F
AU  - Williamson DF
FAU - Croft, J B
AU  - Croft JB
FAU - Ballew, C
AU  - Ballew C
FAU - Byers, T
AU  - Byers T
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Epidemiol
JT  - American journal of epidemiology
JID - 7910653
SB  - IM
MH  - Adipose Tissue
MH  - Adult
MH  - Aged
MH  - Black People
MH  - *Body Constitution
MH  - Body Mass Index
MH  - Female
MH  - Health Surveys
MH  - Humans
MH  - Linear Models
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Myocardial Ischemia/*epidemiology
MH  - Nutrition Surveys
MH  - *Obesity/physiopathology
MH  - Proportional Hazards Models
MH  - Risk Factors
MH  - Skinfold Thickness
MH  - White People
EDAT- 1995/07/01 00:00
MHDA- 1995/07/01 00:01
CRDT- 1995/07/01 00:00
PHST- 1995/07/01 00:00 [pubmed]
PHST- 1995/07/01 00:01 [medline]
PHST- 1995/07/01 00:00 [entrez]
AID - 10.1093/oxfordjournals.aje.a117545 [doi]
PST - ppublish
SO  - Am J Epidemiol. 1995 Jul 1;142(1):53-63. doi: 10.1093/oxfordjournals.aje.a117545.