PMID- 7788612 OWN - NLM STAT- MEDLINE DCOM- 19950727 LR - 20190516 IS - 0706-7437 (Print) IS - 0706-7437 (Linking) VI - 40 IP - 2 DP - 1995 Mar TI - [Atypical depression: evolution toward a specific pharmacologic and efficacious treatment?]. PG - 102-8 AB - The present article reviews different concepts of atypical depression. Of these, major depression associated with panic disorder would have a specific meaning according to some pharmacological and prognosis studies. It seems that this type of depression is quite frequent and has a significantly worse prognosis than major depression alone. Controlled studies comparing the efficacy of tricyclic antidepressants to phenelzine concluded in favour of the latter in general. It is generally thought that atypical depression would respond better to monoamine oxidase inhibitors (MAOI), but it would seem that it is mainly major depression associated with panic disorder that could predict this kind of response to treatment. Second generation antidepressants have not been studied systematically for this purpose even though preliminary reports seem promising. FAU - Dassylva, B AU - Dassylva B AD - Institut Philippe Pinel de Montreal, Quebec. FAU - Fontaine, R AU - Fontaine R LA - fre PT - Comparative Study PT - English Abstract PT - Journal Article PT - Review TT - Depression atypique: evolution vers un traitement pharmacologique specifique et efficace? PL - United States TA - Can J Psychiatry JT - Canadian journal of psychiatry. Revue canadienne de psychiatrie JID - 7904187 RN - 0 (Antidepressive Agents) RN - 0 (Antidepressive Agents, Tricyclic) RN - 0 (Monoamine Oxidase Inhibitors) RN - O408N561GF (Phenelzine) SB - IM MH - Antidepressive Agents/adverse effects/*therapeutic use MH - Antidepressive Agents, Tricyclic/therapeutic use MH - Controlled Clinical Trials as Topic MH - Depressive Disorder/classification/*drug therapy/psychology MH - Humans MH - Monoamine Oxidase Inhibitors/therapeutic use MH - Panic Disorder/classification/*drug therapy/psychology MH - Phenelzine/therapeutic use MH - Prognosis RF - 35 EDAT- 1995/03/01 00:00 MHDA- 1995/03/01 00:01 CRDT- 1995/03/01 00:00 PHST- 1995/03/01 00:00 [pubmed] PHST- 1995/03/01 00:01 [medline] PHST- 1995/03/01 00:00 [entrez] AID - 10.1177/070674379504000209 [doi] PST - ppublish SO - Can J Psychiatry. 1995 Mar;40(2):102-8. doi: 10.1177/070674379504000209.