PMID- 7793193
OWN - NLM
STAT- MEDLINE
DCOM- 19950725
LR  - 20190814
IS  - 0001-5172 (Print)
IS  - 0001-5172 (Linking)
VI  - 39
IP  - 2
DP  - 1995 Feb
TI  - Comparison of cardiac output measurement techniques: thermodilution, Doppler, 
      CO2-rebreathing and the direct Fick method.
PG  - 245-51
AB  - Simultaneously measured cardiac output obtained by thermodilution (TD), 
      transcutaneous suprasternal ultrasonic Doppler (DOP), CO2-rebreathing (CR) and 
      the direct Fick method (FI) were compared in eleven healthy subjects in a supine 
      position (SU), a sitting position (SI), and during sitting exercise at a workload 
      of 50 W (EX). The agreements between the techniques, two by two, were expressed 
      as the bias calculated as the averaged differences between the techniques. 
      Precision was expressed as the standard deviation of the bias. The overall 
      agreement (bias +/- precision) between TD, DOP and CR respectively and FI were 
      2.3 +/- 1.6, -0.1 +/- 1.4, and -0.2 +/- 1.1 l/min. TD overestimated cardiac 
      output consistently in SU, SI and EX. DOP was in-accurate during EX and agreed 
      well with FI in SU and SI. CR agreed closely with FI in SI and EX, but values 
      were underestimated in SU. The overall agreement between DOP and CR, 
      respectively, and TD were 2.5 +/- 2.2 and 2.6 +/- 1.6 l/min. The overall 
      agreement between DOP and CR was 0.1 +/- 1.6 l/min. In conclusion, TD 
      overestimated cardiac output compared to the other techniques and the poor 
      agreement has to be taken into consideration especially in measures of low 
      values. The precision of DOP and CR against FI seems to be within clinically 
      acceptable limits, and these methods may provide interchangeable alternatives to 
      the invasive Fick method.
FAU - Espersen, K
AU  - Espersen K
AD  - Department of Clinical Physiology and Nuclear-Medicine, Herlev Hospital, 
      University of Copenhagen, Denmark.
FAU - Jensen, E W
AU  - Jensen EW
FAU - Rosenborg, D
AU  - Rosenborg D
FAU - Thomsen, J K
AU  - Thomsen JK
FAU - Eliasen, K
AU  - Eliasen K
FAU - Olsen, N V
AU  - Olsen NV
FAU - Kanstrup, I L
AU  - Kanstrup IL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Acta Anaesthesiol Scand
JT  - Acta anaesthesiologica Scandinavica
JID - 0370270
RN  - 142M471B3J (Carbon Dioxide)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Adult
MH  - Aorta/diagnostic imaging/physiology
MH  - Bias
MH  - Blood Flow Velocity
MH  - Carbon Dioxide/*analysis/metabolism
MH  - Cardiac Output/*physiology
MH  - Catheterization, Swan-Ganz
MH  - *Echocardiography, Doppler
MH  - Exercise Test
MH  - Female
MH  - Heart Rate/physiology
MH  - Humans
MH  - Male
MH  - Oxygen/*blood
MH  - Oxygen Consumption/*physiology
MH  - Posture
MH  - Pulmonary Gas Exchange/*physiology
MH  - Respiration/physiology
MH  - Sensitivity and Specificity
MH  - Supine Position
MH  - *Thermodilution
EDAT- 1995/02/01 00:00
MHDA- 1995/02/01 00:01
CRDT- 1995/02/01 00:00
PHST- 1995/02/01 00:00 [pubmed]
PHST- 1995/02/01 00:01 [medline]
PHST- 1995/02/01 00:00 [entrez]
AID - 10.1111/j.1399-6576.1995.tb04051.x [doi]
PST - ppublish
SO  - Acta Anaesthesiol Scand. 1995 Feb;39(2):245-51. doi: 
      10.1111/j.1399-6576.1995.tb04051.x.