PMID- 7810002
OWN - NLM
STAT- MEDLINE
DCOM- 19950131
LR  - 20190913
IS  - 0191-3123 (Print)
IS  - 0191-3123 (Linking)
VI  - 18
IP  - 5
DP  - 1994 Sep-Oct
TI  - Ultrastructural pathology of human T-cell lymphotropic virus type I 
      encephalomyelopathy in a white patient with adult T-cell leukemia/lymphoma.
PG  - 511-8
AB  - A white patient with human T-cell lymphotropic virus type I (HTLV-I)-associated 
      adult T-cell leukemia/lymphoma for 10 years died 4 months after the onset of 
      spastic myelopathy. Ultrastructurally, the neuropathologic findings consisted of 
      dystrophic neurites (spheroids) filled with neurofilaments or electron-dense 
      bodies, intense astrocytic reaction with abundant formation of corpora amylacea, 
      and multilamellar bodies. Demyelination and spongiform change were absent. 
      Viruslike particles resembling HTLV-I were detected adjacent to brain endothelial 
      cells.
FAU - Liberski, P P
AU  - Liberski PP
AD  - Laboratory of Central Nervous System Studies, National Institute of Neurological 
      Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892.
FAU - Rodgers-Johnson, P
AU  - Rodgers-Johnson P
FAU - Yanagihara, R
AU  - Yanagihara R
FAU - Lee, J W
AU  - Lee JW
FAU - Kramer, B S
AU  - Kramer BS
FAU - Piccardo, P
AU  - Piccardo P
FAU - Mora, C A
AU  - Mora CA
FAU - Gibbs, C J Jr
AU  - Gibbs CJ Jr
FAU - Gajdusek, D C
AU  - Gajdusek DC
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Ultrastruct Pathol
JT  - Ultrastructural pathology
JID - 8002867
SB  - IM
MH  - Human T-lymphotropic virus 1/isolation & purification
MH  - Humans
MH  - Leukemia-Lymphoma, Adult T-Cell/*complications
MH  - Male
MH  - Microscopy, Electron
MH  - Middle Aged
MH  - Paraparesis, Tropical Spastic/*pathology/virology
MH  - Spinal Cord/*ultrastructure/virology
EDAT- 1994/09/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1994/09/01 00:00
PHST- 1994/09/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1994/09/01 00:00 [entrez]
AID - 10.3109/01913129409023227 [doi]
PST - ppublish
SO  - Ultrastruct Pathol. 1994 Sep-Oct;18(5):511-8. doi: 10.3109/01913129409023227.