PMID- 7835095 OWN - NLM STAT- MEDLINE DCOM- 19950227 LR - 20180214 IS - 0301-0171 (Print) IS - 0301-0171 (Linking) VI - 69 IP - 1-2 DP - 1995 TI - Absence of terminal telomeric FISH signals in chromosomes from immortal Chinese hamster cells. PG - 87-9 AB - In contrast to normal Chinese hamster cells, terminal telomeric signals were not detectable by fluorescence in situ hybridization (FISH) in their immortalized counterparts, even when a sensitive cooled CCD camera was used for acquiring FISH images. Since the telomeres were detectable by FISH in immortal human cells, this suggests that hamster and human cells might have different mechanisms of telomere processing. FAU - Slijepcevic, P AU - Slijepcevic P AD - Department of Pathology, University of Cambridge, UK. FAU - Bryant, P E AU - Bryant PE LA - eng PT - Journal Article PL - Switzerland TA - Cytogenet Cell Genet JT - Cytogenetics and cell genetics JID - 0367735 SB - IM MH - Animals MH - Base Sequence MH - CHO Cells MH - Cell Line, Transformed MH - *Chromosome Banding MH - *Chromosome Mapping MH - Cricetinae MH - Cricetulus MH - Female MH - Humans MH - Hybrid Cells MH - In Situ Hybridization, Fluorescence/*methods MH - Microscopy, Confocal MH - *Repetitive Sequences, Nucleic Acid MH - Telomere/*ultrastructure EDAT- 1995/01/01 00:00 MHDA- 1995/01/01 00:01 CRDT- 1995/01/01 00:00 PHST- 1995/01/01 00:00 [pubmed] PHST- 1995/01/01 00:01 [medline] PHST- 1995/01/01 00:00 [entrez] AID - 10.1159/000133944 [doi] PST - ppublish SO - Cytogenet Cell Genet. 1995;69(1-2):87-9. doi: 10.1159/000133944.