PMID- 7841444
OWN - NLM
STAT- MEDLINE
DCOM- 19950303
LR  - 20141120
IS  - 0916-8478 (Print)
IS  - 0916-8478 (Linking)
VI  - 39
IP  - 3
DP  - 1994 Sep
TI  - Fluorescence in situ hybridization analysis of chromosomal localization of three 
      human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1.
PG  - 337-43
AB  - Chromosomal localization of three human cytochrome P450 genes belonging to the 
      CYP2C subfamily (CYP2C8, 2C9, and 2C10) was identified by fluorescence in situ 
      hybridization (FISH). An original MP-8 clone was used as a DNA probe for the 
      assignment of the CYP2C10 gene, while two cDNA probes, a 1.37 kb fragment of 
      CYP2C8 and a 1.19 kb fragment of CYP2C9, were obtained after amplifying the 
      predicted fragments (MP-20 and MP-4 clones, respectively) by polymerase chain 
      reaction using a single human liver cDNA library. The results showed that three 
      human CYP2C8, 2C9, and 2C10 cDNAs were located at the same subchromosomal region, 
      10q24.1.
FAU - Inoue, K
AU  - Inoue K
AD  - Osaka Prefectural Institute of Public Health, Japan.
FAU - Inazawa, J
AU  - Inazawa J
FAU - Suzuki, Y
AU  - Suzuki Y
FAU - Shimada, T
AU  - Shimada T
FAU - Yamazaki, H
AU  - Yamazaki H
FAU - Guengerich, F P
AU  - Guengerich FP
FAU - Abe, T
AU  - Abe T
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Jpn J Hum Genet
JT  - The Japanese journal of human genetics
JID - 9213239
RN  - 9035-51-2 (Cytochrome P-450 Enzyme System)
RN  - EC 1.14.- (Steroid Hydroxylases)
RN  - EC 1.14.13.- (CYP2C9 protein, human)
RN  - EC 1.14.13.- (Cytochrome P-450 CYP2C9)
RN  - EC 1.14.14.1 (Aryl Hydrocarbon Hydroxylases)
RN  - EC 1.14.14.1 (CYP2C8 protein, human)
RN  - EC 1.14.14.1 (Cytochrome P-450 CYP2C8)
RN  - EC 1.14.14.1 (Steroid 16-alpha-Hydroxylase)
SB  - IM
GS  - CYP2C10
GS  - CYP2C8
GS  - CYP2C9
MH  - *Aryl Hydrocarbon Hydroxylases
MH  - Base Sequence
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 10
MH  - Cytochrome P-450 CYP2C8
MH  - Cytochrome P-450 CYP2C9
MH  - Cytochrome P-450 Enzyme System/*genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
MH  - *Steroid 16-alpha-Hydroxylase
MH  - Steroid Hydroxylases/*genetics
EDAT- 1994/09/01 00:00
MHDA- 1994/09/01 00:01
CRDT- 1994/09/01 00:00
PHST- 1994/09/01 00:00 [pubmed]
PHST- 1994/09/01 00:01 [medline]
PHST- 1994/09/01 00:00 [entrez]
AID - 10.1007/BF01874052 [doi]
PST - ppublish
SO  - Jpn J Hum Genet. 1994 Sep;39(3):337-43. doi: 10.1007/BF01874052.