PMID- 7842737
OWN - NLM
STAT- MEDLINE
DCOM- 19950307
LR  - 20180214
IS  - 0301-0171 (Print)
IS  - 0301-0171 (Linking)
VI  - 68
IP  - 3-4
DP  - 1995
TI  - Incidence of low-fluorescence alpha satellite region on chromosome 21 escaping 
      detection of aneuploidy at interphase by FISH.
PG  - 203-6
AB  - Aneuploidy detection for chromosome 21 by fluorescence in situ hybridization 
      (FISH) to interphase nuclei using a probe specific for the alphoid DNA sequences 
      D21Z1/D13Z1 should be avoided. An extreme heteromorphism, resulting in 
      misdiagnosis if interphase FISH is the only test employed, may be far more 
      frequent (4/101) than expected.
FAU - Bossuyt, P J
AU  - Bossuyt PJ
AD  - Department of Medical Genetics, University of Antwerp-U.I.A. Wilrijk, Belgium.
FAU - Van Tienen, M N
AU  - Van Tienen MN
FAU - De Gruyter, L
AU  - De Gruyter L
FAU - Smets, V
AU  - Smets V
FAU - Dumon, J
AU  - Dumon J
FAU - Wauters, J G
AU  - Wauters JG
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Cytogenet Cell Genet
JT  - Cytogenetics and cell genetics
JID - 0367735
SB  - IM
MH  - *Aneuploidy
MH  - *Chromosomes, Human, Pair 21
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Interphase/genetics
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 10.1159/000133914 [doi]
PST - ppublish
SO  - Cytogenet Cell Genet. 1995;68(3-4):203-6. doi: 10.1159/000133914.