PMID- 7845003 OWN - NLM STAT- MEDLINE DCOM- 19950306 LR - 20130304 IS - 0887-6924 (Print) IS - 0887-6924 (Linking) VI - 9 IP - 1 DP - 1995 Jan TI - FISH diagnosis of t(8;21) in a myelodysplasia secondary to Hodgkin lymphoma. PG - 107-8 AB - A t(8;21)(q22;q22) translocation without blood and bone marrow invasion by immature myeloid precursors was suspected in a conventional karyotype and confirmed by fluorescence in situ hybridization (FISH) with chromosome 8 and 21 painting in a patient previously treated for Hodgkin's lymphoma. Six weeks later, the diagnosis was confirmed by the onset of acute myeloid leukemia (AML) M2 with a t(8;21) in the bone marrow. FAU - Bernheim, A AU - Bernheim A AD - Laboratoire de Cytogenetique et de Genetique Oncologiques, URA 1158 CNRS, Villejuif, France. FAU - Duverger, A AU - Duverger A FAU - Fouquet, F AU - Fouquet F FAU - Bayle, C AU - Bayle C FAU - Oberlin, O AU - Oberlin O LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Leukemia JT - Leukemia JID - 8704895 SB - IM MH - *Chromosomes, Human, Pair 21 MH - *Chromosomes, Human, Pair 8 MH - Hodgkin Disease/*genetics MH - Humans MH - *In Situ Hybridization, Fluorescence MH - Infant, Newborn MH - Leukemia, Myeloid, Acute/*genetics MH - Male MH - *Translocation, Genetic EDAT- 1995/01/01 00:00 MHDA- 1995/01/01 00:01 CRDT- 1995/01/01 00:00 PHST- 1995/01/01 00:00 [pubmed] PHST- 1995/01/01 00:01 [medline] PHST- 1995/01/01 00:00 [entrez] PST - ppublish SO - Leukemia. 1995 Jan;9(1):107-8.