PMID- 7845529
OWN - NLM
STAT- MEDLINE
DCOM- 19950308
LR  - 20190920
IS  - 0305-1846 (Print)
IS  - 0305-1846 (Linking)
VI  - 20
IP  - 5
DP  - 1994 Oct
TI  - Detection of numerical chromosome aberrations in brain tumours by fluorescence in 
      situ hybridization on smear preparations of small tumour biopsies.
PG  - 432-8
AB  - We present a technique for the preparation and interphase cytogenetic analysis of 
      native tumour cell nuclei from smear preparations of small biopsies of human 
      brain tumours. The presence of tumour-specific numerical chromosome aberrations 
      can be determined by fluorescence in situ hybridization (FISH) analysis using 
      chromosome-specific repetitive DNA probes. The FISH analysis of smear 
      preparations provides cytogenetic information about brain tumour samples, within 
      2 days, avoiding time-consuming and artefact-prone tumour cell culture.
FAU - Low, M
AU  - Low M
AD  - Institute of Human Genetics, Saarland University, Homburg/Saar, Germany.
FAU - Feiden, W
AU  - Feiden W
FAU - Moringlane, J R
AU  - Moringlane JR
FAU - Zang, K D
AU  - Zang KD
FAU - Henn, W
AU  - Henn W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Neuropathol Appl Neurobiol
JT  - Neuropathology and applied neurobiology
JID - 7609829
SB  - IM
MH  - Biopsy
MH  - Brain Neoplasms/*genetics/pathology
MH  - *Chromosome Aberrations
MH  - Chromosomes, Human, Pair 1
MH  - Chromosomes, Human, Pair 7
MH  - Cytogenetics/methods
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Interphase
EDAT- 1994/10/01 00:00
MHDA- 1994/10/01 00:01
CRDT- 1994/10/01 00:00
PHST- 1994/10/01 00:00 [pubmed]
PHST- 1994/10/01 00:01 [medline]
PHST- 1994/10/01 00:00 [entrez]
AID - 10.1111/j.1365-2990.1994.tb00993.x [doi]
PST - ppublish
SO  - Neuropathol Appl Neurobiol. 1994 Oct;20(5):432-8. doi: 
      10.1111/j.1365-2990.1994.tb00993.x.