PMID- 7846222 OWN - NLM STAT- MEDLINE DCOM- 19950308 LR - 20190830 IS - 0048-5772 (Print) IS - 0048-5772 (Linking) VI - 31 IP - 6 DP - 1994 Nov TI - Two separate frontal components in the N1 wave of the human auditory evoked response. PG - 611-5 AB - Scalp current density analysis of the auditory evoked response to 1-kHz tone bursts delivered at various interstimulus intervals (ISIs) (from 1 s to 2 min in separate runs) shows that two different frontal components can be observed and functionally dissociated in the N1 time range: one is elicited for all ISIs, peaks at about 95 ms poststimulus, and has a full recovery time below 8 s; the second is elicited only by infrequent stimuli (ISIs > 4 s), peaks around 140 ms, and significantly increases in amplitude with increasing ISIs. The first component can be considered a new obligatory component in N1 elicited simultaneously with the responses in auditory cortex; the later component could correspond to the orienting Component III of Naatanen and Picton (1987). FAU - Alcaini, M AU - Alcaini M AD - Brain Signals and Processes Laboratory, INSERM-U280, Lyon, France. FAU - Giard, M H AU - Giard MH FAU - Thevenet, M AU - Thevenet M FAU - Pernier, J AU - Pernier J LA - eng PT - Journal Article PL - United States TA - Psychophysiology JT - Psychophysiology JID - 0142657 SB - IM MH - Acoustic Stimulation MH - Adolescent MH - Adult MH - Arousal/*physiology MH - Attention/*physiology MH - Brain Mapping MH - Evoked Potentials, Auditory/*physiology MH - Female MH - Frontal Lobe/*physiology MH - Humans MH - Male MH - Pitch Discrimination/physiology MH - Reference Values EDAT- 1994/11/01 00:00 MHDA- 1994/11/01 00:01 CRDT- 1994/11/01 00:00 PHST- 1994/11/01 00:00 [pubmed] PHST- 1994/11/01 00:01 [medline] PHST- 1994/11/01 00:00 [entrez] AID - 10.1111/j.1469-8986.1994.tb02354.x [doi] PST - ppublish SO - Psychophysiology. 1994 Nov;31(6):611-5. doi: 10.1111/j.1469-8986.1994.tb02354.x.