PMID- 7851462
OWN - NLM
STAT- MEDLINE
DCOM- 19950316
LR  - 20180214
IS  - 0014-312X (Print)
IS  - 0014-312X (Linking)
VI  - 26
IP  - 6
DP  - 1994
TI  - Effect of vagotomy on cholecystokinin release and gallbladder contraction in 
      patients with complicated duodenal ulcer.
PG  - 362-71
AB  - In this prospective study, we investigated gallbladder (GB) contraction and 
      plasma cholecystokinin (CCK) levels in response to food intake before and 1 month 
      after vagotomy in 27 patients with complicated duodenal ulcer. Highly selective 
      vagotomy (HSV) was carried out in 6 patients, truncal vagotomy and pyloroplasty 
      (TVP) in 4, truncal vagotomy and antrectomy (TVA) in 7, selective vagotomy and 
      pyloroplasty (SVP) in 5 and selective vagotomy and antrectomy (SVA) in another 5 
      patients with pyloric stenosis. The results of our studies indicated that (1) 
      basal plasma CCK levels increased significantly after vagotomy, (2) none of the 
      vagotomy operations altered the integrated CCK response, (3) unlike HSV, SVA and 
      TVA, SVP and TVP decreased GB emptying and (4) antrectomy significantly enhanced 
      CCK release after food intake. We concluded from these findings that the 
      operative procedure of HSV, SVA or TVA to circumvent bile stasis-related 
      postvagotomy cholelithiasis is superior to SVP or TVP in the surgical treatment 
      of complicated duodenal ulcer.
FAU - Huang, Y S
AU  - Huang YS
AD  - Department of Surgery, Kaohsiung Medical College, Taiwan.
FAU - Huang, T J
AU  - Huang TJ
FAU - McKay, D
AU  - McKay D
FAU - Rayford, P L
AU  - Rayford PL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Switzerland
TA  - Eur Surg Res
JT  - European surgical research. Europaische chirurgische Forschung. Recherches 
      chirurgicales europeennes
JID - 0174752
RN  - 9011-97-6 (Cholecystokinin)
SB  - IM
MH  - Cholecystokinin/*blood
MH  - Duodenal Ulcer/blood/*physiopathology/*surgery
MH  - Female
MH  - Gallbladder/physiology
MH  - Gallbladder Emptying/*physiology
MH  - Humans
MH  - Male
MH  - Muscle Contraction
MH  - Prospective Studies
MH  - Radioimmunoassay
MH  - *Vagotomy/methods
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
AID - 10.1159/000129357 [doi]
PST - ppublish
SO  - Eur Surg Res. 1994;26(6):362-71. doi: 10.1159/000129357.