PMID- 7866272
OWN - NLM
STAT- MEDLINE
DCOM- 19950328
LR  - 20190116
IS  - 1042-8194 (Print)
IS  - 1026-8022 (Linking)
VI  - 15
IP  - 3-4
DP  - 1994 Oct
TI  - Human herpesvirus 6 and pneumonia.
PG  - 235-41
AB  - Studies of lung tissues and bronchoalveolar lavage specimens from patients with 
      pneumonia have led some investigators to propose that human herpesvirus 6 (HHV-6) 
      can cause pneumonia. As the etiologic role of HHV-6 in pneumonia remains poorly 
      defined, cases of pneumonia that are associated with pulmonary HHV-6 infection 
      are best described as HHV-6-associated pneumonias. The clinical spectrum of 
      HHV-6-associated pneumonia encompasses both mild and severe cases. Most cases 
      reported so far occurred in immunosuppressed individuals following bone marrow 
      transplantation or HIV infection. Some studies have identified coinfections with 
      HHV-6 and other viruses in a surprising number of HHV-6-associated pneumonias. 
      Although no systematic evaluation of treatment regimens is available at this 
      time, coincidental administration of antiviral drugs did not generally result in 
      clinical improvement. Controlled, prospective studies are needed to understand 
      the clinical presentation, clinical course, etiology, diagnosis and treatment of 
      HHV-6-associated pneumonias.
FAU - Cone, R W
AU  - Cone RW
AD  - Department of Laboratory Medicine, University of Washington, Seattle.
FAU - Huang, M L
AU  - Huang ML
FAU - Hackman, R C
AU  - Hackman RC
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Leuk Lymphoma
JT  - Leukemia & lymphoma
JID - 9007422
SB  - IM
MH  - Adult
MH  - Animals
MH  - Bone Marrow Transplantation/adverse effects
MH  - HIV Infections/complications/virology
MH  - Herpesviridae Infections/immunology/*virology
MH  - *Herpesvirus 6, Human
MH  - Humans
MH  - Immunocompetence
MH  - Infant, Newborn
MH  - Male
MH  - Mice
MH  - Pneumonia, Viral/immunology/*virology
RF  - 56
EDAT- 1994/10/01 00:00
MHDA- 1994/10/01 00:01
CRDT- 1994/10/01 00:00
PHST- 1994/10/01 00:00 [pubmed]
PHST- 1994/10/01 00:01 [medline]
PHST- 1994/10/01 00:00 [entrez]
AID - 10.3109/10428199409049719 [doi]
PST - ppublish
SO  - Leuk Lymphoma. 1994 Oct;15(3-4):235-41. doi: 10.3109/10428199409049719.