PMID- 7868548
OWN - NLM
STAT- MEDLINE
DCOM- 19950330
LR  - 20071115
IS  - 0004-5772 (Print)
IS  - 0004-5772 (Linking)
VI  - 42
IP  - 8
DP  - 1994 Aug
TI  - Ventricular late potentials after thrombolysis.
PG  - 597-8
AB  - High frequency low amplitude signals that prolong the terminal portion of the QRS 
      complex in the electrocardiogram are termed late potentials (LPs). It has been 
      established for quite some time that the presence of LPs after acute myocardial 
      infarction (AMI) is associated with an increased risk of ventricular 
      tachyarrythmias and sudden cardiac death (SCD), and vice versa. It is also known 
      that thrombolytic therapy after AMI significantly decreased the incidence of 
      ventricular tachyarrythmias and SCD. The object of this study was to find out 
      whether thrombolysis in AMI decreased the incidence of LPs. Fifty two male 
      patients of the age group 41-46 years with first anterior wall AMI were studied. 
      Thirty of them presented within 6 hours of chest pain and were given intravenous 
      streptokinase (IVSK) in addition to conventional therapy. The remaining 22 
      received conventional therapy but no thrombolysis. There was no significant 
      difference in these two groups regarding age, CKMB, hypertension, diabetes, 
      smoking, prior use of beta blockers, and ejection fraction. Eight out of the 30 
      patients receiving IVSK were positive for LPs as against 13 out of the 22 in the 
      control group. This difference was statistically significant (p > 0.02 < 0.01). 
      Thus thrombolysis in the early hours of anterior AMI diminishes the incidence of 
      LPs.
FAU - Kar, A K
AU  - Kar AK
AD  - Dept of Cardiology, Institute of Postgraduate Medical Education & Research 
      Centre, Calcutta.
FAU - Chatterjee, A
AU  - Chatterjee A
FAU - Roy, S
AU  - Roy S
FAU - Sarkar, A
AU  - Sarkar A
FAU - Panja, M
AU  - Panja M
LA  - eng
PT  - Journal Article
PL  - India
TA  - J Assoc Physicians India
JT  - The Journal of the Association of Physicians of India
JID - 7505585
SB  - IM
CIN - J Assoc Physicians India. 1994 Aug;42(8):596. PMID: 7868547
MH  - Adult
MH  - Aged
MH  - Arrhythmias, Cardiac/etiology
MH  - *Electrocardiography
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/complications/*drug therapy/physiopathology
MH  - *Thrombolytic Therapy
EDAT- 1994/08/01 00:00
MHDA- 1994/08/01 00:01
CRDT- 1994/08/01 00:00
PHST- 1994/08/01 00:00 [pubmed]
PHST- 1994/08/01 00:01 [medline]
PHST- 1994/08/01 00:00 [entrez]
PST - ppublish
SO  - J Assoc Physicians India. 1994 Aug;42(8):597-8.