PMID- 7874399
OWN - NLM
STAT- MEDLINE
DCOM- 19950406
LR  - 20191101
IS  - 0960-5428 (Print)
IS  - 0960-5428 (Linking)
VI  - 4
IP  - 3
DP  - 1994
TI  - Neuroglial-specific factors and the regulation of retrovirus transcription.
PG  - 305-18
AB  - Retroviruses have been implicated as causative agents of a variety of human 
      diseases including malignancy, immune system dysfunction, and neurologic 
      disorders. Despite the isolation of various retroviral agents from patients 
      suffering from malignant neoplasias and neurologic disorders, only the human 
      T-cell lymphotropic virus type I (HTLV-I) and the human immunodeficiency virus 
      (HIV) have been definitively accepted as etiologic agents of human disease 
      (Hjelle, 1991; Gessain and Gout, 1992; Rosenblatt, 1993). Because of their 
      increasingly defined roles in disease progression, the replication of HTLV-I and 
      HIV is an important focus for understanding the pathogenic processes resulting 
      from viral infection. Of particular interest are the molecular mechanisms by 
      which expression of retroviral genomes is regulated by their regulatory units, 
      the long terminal repeats (LTR), in a manner specific to the cellular targets 
      which they infect.
FAU - Tillmann, M
AU  - Tillmann M
AD  - Department of Microbiology and Immunology, Pennsylvania State University, College 
      of Medicine, Hershey 17033.
FAU - Krebs, F C
AU  - Krebs FC
FAU - Wessner, R
AU  - Wessner R
FAU - Pomeroy, S M
AU  - Pomeroy SM
FAU - Goodenow, M M
AU  - Goodenow MM
FAU - Wigdahl, B
AU  - Wigdahl B
LA  - eng
GR  - CA 54559/CA/NCI NIH HHS/United States
GR  - NS 27405/NS/NINDS NIH HHS/United States
GR  - NS 32092/NS/NINDS NIH HHS/United States
GR  - etc.
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PT  - Review
PL  - England
TA  - Adv Neuroimmunol
JT  - Advances in neuroimmunology
JID - 9108376
RN  - 0 (Gene Products, tax)
RN  - 0 (Recombinant Fusion Proteins)
RN  - 0 (Transcription Factors)
SB  - IM
GS  - env
GS  - gag
GS  - pol
MH  - AIDS Dementia Complex/pathology/virology
MH  - Base Sequence
MH  - Cells, Cultured
MH  - *Gene Expression Regulation, Viral
MH  - Gene Products, tax/physiology
MH  - Genome, Viral
MH  - HIV Long Terminal Repeat
MH  - HIV-1/*physiology
MH  - Human T-lymphotropic virus 1/*physiology
MH  - Humans
MH  - Microglia/physiology/virology
MH  - Models, Biological
MH  - Molecular Sequence Data
MH  - Neuroglia/*physiology/virology
MH  - Recombinant Fusion Proteins/genetics/metabolism
MH  - *Repetitive Sequences, Nucleic Acid
MH  - Transcription Factors/physiology
MH  - *Transcription, Genetic
MH  - Transcriptional Activation
RF  - 32
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
AID - 10.1016/s0960-5428(06)80271-8 [doi]
PST - ppublish
SO  - Adv Neuroimmunol. 1994;4(3):305-18. doi: 10.1016/s0960-5428(06)80271-8.