PMID- 7882109
OWN - NLM
STAT- MEDLINE
DCOM- 19950410
LR  - 20061115
IS  - 1077-9450 (Print)
IS  - 1077-9450 (Linking)
VI  - 8
IP  - 4
DP  - 1995 Apr 1
TI  - Risk factors for maternal HTLV-I infection in French Guiana: high HTLV-I 
      prevalence in the Noir Marron population.
PG  - 420-5
AB  - The aim of this study was to compare rates of human T-cell lymphotropic virus 
      type I (HTLV-I) seroprevalence in pregnant women belonging to different ethnic 
      groups in French Guiana and to determine the risk factors associated with HTLV-I 
      seropositivity. All 1,873 deliveries between 1 July 1991 and 30 June 1993 in the 
      only gynecologic and obstetric unit at Saint Laurent du Maroni were enrolled. 
      Serologic status could be established for 1,727 women, with 75 (4.3%) being 
      HTLV-I seropositive. The HTLV-I seroprevalence rate differed significantly 
      between ethnic groups: 5.7% for Noir-Marron (70/1,302), 6.3% for Haitian (3/50), 
      and 0% for Creole (126), Amerindians (166), and Hmong (64). In Noir-Marron 
      pregnant women, HTLV-I seropositivity was associated with a maternal age of > 35 
      years [odds ratio (OR), 3.3; 95% confidence interval (CI), 1.4-7.6], prior 
      miscarriage (OR, 1.7; CI, 1-2.8), prior cesarean section (OR, 2.1; CI, 1.1-4.0), 
      a parity > 4 (OR, 4.0; CI, 1.8-8.8), a gravidity > 6 (OR, 4.2; CI, 2.0-7.2), and 
      a negative Rhesus factor (OR, 2.2; CI, 1.1-4.5). Two separate stepwise logistic 
      regressions were done because gravidity and parity were highly correlated. HTLV-I 
      seropositivity remained associated with a gravidity > 6 (OR, 3.9; CI, 2.1-7.4) 
      and a negative Rhesus factor (OR, 2.6; CI, 1.2-5.3) for the first model and with 
      a parity > 4 (OR, 4.1; CI, 1.9-9.0) and a negative Rhesus factor (OR, 2.5; CI, 
      1.2-5.1) for the second model.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Tuppin, P
AU  - Tuppin P
AD  - Unite d'Epidemiologie des Virus Oncogenes, Institut Pasteur, Paris, France.
FAU - Lepere, J F
AU  - Lepere JF
FAU - Carles, G
AU  - Carles G
FAU - Ureta-Vidal, A
AU  - Ureta-Vidal A
FAU - Gerard, Y
AU  - Gerard Y
FAU - Peneau, C
AU  - Peneau C
FAU - Tortevoye, P
AU  - Tortevoye P
FAU - de The, G
AU  - de The G
FAU - Moreau, J P
AU  - Moreau JP
FAU - Gessain, A
AU  - Gessain A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Acquir Immune Defic Syndr Hum Retrovirol
JT  - Journal of acquired immune deficiency syndromes and human retrovirology : 
      official publication of the International Retrovirology Association
JID - 9501482
RN  - 0 (HTLV-I Antibodies)
SB  - IM
MH  - Adult
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - French Guiana/epidemiology
MH  - HTLV-I Antibodies/analysis
MH  - HTLV-I Infections/epidemiology/*ethnology/transmission
MH  - *Human T-lymphotropic virus 1
MH  - Humans
MH  - Odds Ratio
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/epidemiology/*ethnology
MH  - Prevalence
MH  - Risk Factors
MH  - Seroepidemiologic Studies
EDAT- 1995/04/01 00:00
MHDA- 1995/04/01 00:01
CRDT- 1995/04/01 00:00
PHST- 1995/04/01 00:00 [pubmed]
PHST- 1995/04/01 00:01 [medline]
PHST- 1995/04/01 00:00 [entrez]
PST - ppublish
SO  - J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Apr 1;8(4):420-5.