PMID- 7888069
OWN - NLM
STAT- MEDLINE
DCOM- 19950420
LR  - 20051116
IS  - 0167-5699 (Print)
IS  - 0167-5699 (Linking)
VI  - 16
IP  - 2
DP  - 1995 Feb
TI  - Human herpesvirus 6 in AIDS.
PG  - 67-71
AB  - Multiple lines of clinical and experimental evidence suggest that human 
      herpesvirus 6 (HHV-6) may act as an accelerating factor in the natural history of 
      human immunodeficiency virus (HIV) infection. Although, in common with HIV, HHV-6 
      has a primary tropism for CD4+ T cells, its potential effects on the immune 
      system are broader. For instance, HHV-6 can also infect and kill CD8+ T cells, 
      natural killer cells and mononuclear phagocytes. Here, Paolo Lusso and Robert 
      Gallo suggest that understanding the immunopathogenic role of HHV-6 in the course 
      of HIV infection may shed new light on the complex mechanisms of disease 
      progression in AIDS.
FAU - Lusso, P
AU  - Lusso P
AD  - Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes 
      of Health, Bethesda, MD 20892.
FAU - Gallo, R C
AU  - Gallo RC
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Immunol Today
JT  - Immunology today
JID - 8008346
SB  - IM
MH  - Acquired Immunodeficiency Syndrome/*virology
MH  - Herpesviridae Infections/*complications
MH  - Herpesvirus 6, Human/*isolation & purification
MH  - Humans
RF  - 35
EDAT- 1995/02/01 00:00
MHDA- 1995/02/01 00:01
CRDT- 1995/02/01 00:00
PHST- 1995/02/01 00:00 [pubmed]
PHST- 1995/02/01 00:01 [medline]
PHST- 1995/02/01 00:00 [entrez]
AID - 0167-5699(95)80090-5 [pii]
AID - 10.1016/0167-5699(95)80090-5 [doi]
PST - ppublish
SO  - Immunol Today. 1995 Feb;16(2):67-71. doi: 10.1016/0167-5699(95)80090-5.