PMID- 7889647
OWN - NLM
STAT- MEDLINE
DCOM- 19950418
LR  - 20190816
IS  - 0009-9163 (Print)
IS  - 0009-9163 (Linking)
VI  - 46
IP  - 5
DP  - 1994 Nov
TI  - Identification of a non-fluorescent isodicentric Y chromosome by molecular 
      cytogenetic techniques.
PG  - 364-7
AB  - A 12 1/2-month-old girl was referred because of short stature, short neck, large 
      internipple distance and simian crease on her right hand. By routine cytogenetic 
      techniques the presence of an unidentifiable marker chromosome and loss of one X 
      chromosome was noted (i.e. 45, X/46, X, mar/47, X, mar, +mar). By fluorescence in 
      situ hybridization (FISH) technique, the marker chromosome was identified as an 
      isodicentric non-fluorescent Y chromosome ((45, X/46, X, idic (Ynf)/47, X, idic 
      (Ynf), +idic (Ynf)). Although the clinical significance of this finding cannot be 
      assessed at present, possible development of gonadoblastoma in such cases is a 
      major concern and warrants follow-up evaluations.
FAU - Macera, M J
AU  - Macera MJ
AD  - Long Island College Hospital, SUNY Health Science Center at Brooklyn.
FAU - Sherman, J
AU  - Sherman J
FAU - Shah, H O
AU  - Shah HO
FAU - Blumberg, D L
AU  - Blumberg DL
FAU - Buttice, L S
AU  - Buttice LS
FAU - Lin, J H
AU  - Lin JH
FAU - Verma, R S
AU  - Verma RS
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Denmark
TA  - Clin Genet
JT  - Clinical genetics
JID - 0253664
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Chromosome Banding
MH  - Female
MH  - Genetic Markers
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Infant
MH  - Turner Syndrome/diagnosis/*genetics
MH  - *Y Chromosome/genetics
EDAT- 1994/11/01 00:00
MHDA- 1994/11/01 00:01
CRDT- 1994/11/01 00:00
PHST- 1994/11/01 00:00 [pubmed]
PHST- 1994/11/01 00:01 [medline]
PHST- 1994/11/01 00:00 [entrez]
AID - 10.1111/j.1399-0004.1994.tb04180.x [doi]
PST - ppublish
SO  - Clin Genet. 1994 Nov;46(5):364-7. doi: 10.1111/j.1399-0004.1994.tb04180.x.