PMID- 7896416
OWN - NLM
STAT- MEDLINE
DCOM- 19950427
LR  - 20190909
IS  - 0340-0131 (Print)
IS  - 0340-0131 (Linking)
VI  - 66
IP  - 5
DP  - 1994
TI  - Immunological and respiratory reactions in workers exposed to organic dusts.
PG  - 317-24
AB  - The relationship of skin reactivity and serum immunoglobulin E (IgE) levels to 
      the prevalence of chronic respiratory symptoms and to ventilatory capacity is 
      examined in workers exposed to different organic aerosols. The results from group 
      of control workers similarly tested are also presented. Workers exposed to 
      occupational allergens had positive skin tests more frequently than did controls, 
      except for soy bean workers. Workers with positive skin tests to occupational 
      allergens had a higher prevalence of almost all symptoms than those with negative 
      skin tests although the differences did not always reach statistical 
      significance. Workers with positive skin reactions in general had significantly 
      higher serum IgE levels than did workers with negative skin reactions. There were 
      across-shift reductions of ventilatory capacity in all groups of exposed workers, 
      varying for forced vital capacity from 1.7% to 13.3%, for forced expiratory 
      volume from 0.4%-21.9%, for maximum flow rates at 50% from 1.5% to 16.1% and for 
      maximum flow rates at the last 25% of control vital capacity from 0% to 24.9%. 
      There was, however, no correlation between acute and chronic lung function 
      changes and skin reactivity or IgE values. Our data suggest that although 
      exposure to organic aerosols may be associated with frequent immunologic 
      reactions, these findings do not predict objective respiratory impairment.
FAU - Zuskin, E
AU  - Zuskin E
AD  - Andrija Stampar School of Public Health, Medical Faculty, University of Zagreb, 
      Croatia.
FAU - Schachter, E N
AU  - Schachter EN
FAU - Kanceljak, B
AU  - Kanceljak B
FAU - Mustajbegovic, J
AU  - Mustajbegovic J
FAU - Witek, T J
AU  - Witek TJ
LA  - eng
GR  - JBP 733/PHS HHS/United States
GR  - R01 OHO-2593-04/OH/NIOSH CDC HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Germany
TA  - Int Arch Occup Environ Health
JT  - International archives of occupational and environmental health
JID - 7512134
RN  - 0 (Dust)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - *Agriculture
MH  - Chronic Disease
MH  - Dust/*adverse effects
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Male
MH  - Matched-Pair Analysis
MH  - *Occupational Exposure
MH  - Respiratory Mechanics
MH  - Respiratory Tract Diseases/*etiology/physiopathology
MH  - Sex Factors
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
AID - 10.1007/BF00378364 [doi]
PST - ppublish
SO  - Int Arch Occup Environ Health. 1994;66(5):317-24. doi: 10.1007/BF00378364.