PMID- 7902396
OWN - NLM
STAT- MEDLINE
DCOM- 19940106
LR  - 20190909
IS  - 0955-3002 (Print)
IS  - 0955-3002 (Linking)
VI  - 64
IP  - 5
DP  - 1993 Nov
TI  - Frequency of reciprocal translocations and dicentrics induced in human blood 
      lymphocytes by X-irradiation as determined by fluorescence in situ hybridization.
PG  - 565-9
AB  - This study was designed to test the scoring efficiency of reciprocal 
      translocations and dicentrics induced by X-irradiation in vitro using the 
      fluorescence in situ hybridization (FISH) technique. An excess was found in the 
      frequencies of reciprocal translocations relative to those of dicentrics by 
      measurement with FISH at the first cell division after irradiation 
      (translocation:dicentric approximately 60:40). However, when the same metaphases 
      were also evaluated sequentially by a conventional staining method, the ratio of 
      about 50:50 was restored. This was due in part to misclassification of certain 
      dicentrics as reciprocal translocations by the FISH technique.
FAU - Nakano, M
AU  - Nakano M
AD  - Department of Genetics, Radiation Effects Research Foundation, Hiroshima, Japan.
FAU - Nakashima, E
AU  - Nakashima E
FAU - Pawel, D J
AU  - Pawel DJ
FAU - Kodama, Y
AU  - Kodama Y
FAU - Awa, A
AU  - Awa A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - England
TA  - Int J Radiat Biol
JT  - International journal of radiation biology
JID - 8809243
SB  - IM
MH  - Adult
MH  - Blood
MH  - *Chromosome Aberrations
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - In Vitro Techniques
MH  - Lymphocytes/*radiation effects
MH  - Radiation Genetics
MH  - Translocation, Genetic
EDAT- 1993/11/01 00:00
MHDA- 1993/11/01 00:01
CRDT- 1993/11/01 00:00
PHST- 1993/11/01 00:00 [pubmed]
PHST- 1993/11/01 00:01 [medline]
PHST- 1993/11/01 00:00 [entrez]
AID - U70P7RH9V31H27FP [pii]
AID - 10.1080/09553009314551781 [doi]
PST - ppublish
SO  - Int J Radiat Biol. 1993 Nov;64(5):565-9. doi: 10.1080/09553009314551781.