PMID- 7911562
OWN - NLM
STAT- MEDLINE
DCOM- 19940714
LR  - 20131121
IS  - 0375-9393 (Print)
IS  - 0375-9393 (Linking)
VI  - 60
IP  - 1-2
DP  - 1994 Jan-Feb
TI  - [Post-tetanic count after 50 and 100 Hz tetanic stimulation for monitoring deep 
      neuromuscular blockade with vecuronium].
PG  - 49-53
AB  - For monitoring of vecuronium profound neuromuscular blockade post-tetanic count 
      (PTC) following tetanic stimulation at frequency of 50 and 100 Hz was employed in 
      25 ASA I-II patients submitted to elective surgery, to evaluate the differences 
      between the two patterns of stimulation and the possible clinical utility of the 
      latter pattern of stimulation. The drugs employed for anaesthesia were: diazepam 
      0.15 mg kg-1 in premedication, thiopental 4-5 mg kg-1 for induction, 
      suxamethonium 1.5 mg kg-1 for tracheal intubation. Anaesthesia was maintained 
      with N2 + O2 (2:1). Analgesia was obtained with fentanyl at usual doses, and 
      muscular relaxation with vecuronium. The ulnar nerve was stimulated at the wrist 
      with Digistim III Plus and the responses evaluated by tactile method. The pattern 
      of stimulation used was a cyclic one, as described by Howardy Hansen et al. The 
      first dose of vecuronium (0.06 mg kg-1) was administered at recovery from 
      suxamethonium (clinically evaluated) and the other doses (0.06 mg kg-1) when the 
      third response to a train of four appeared. The results show that the PTC 
      following 100 Hz tetanus was greater than the PTC following 50 Hz tetanic 
      stimulation (P < 0.01). The results also show that PTC following 100 Hz tetanus 
      leads to underestimate neuromuscular blockade; yet maybe it has any clinical 
      employment in selected surgical situations such as middle ear and eye surgery, 
      microvascular surgery, neurosurgery.
FAU - Barbone, G
AU  - Barbone G
AD  - Istituto di Anestesiologia e Rianimazione, Universita di Bari.
FAU - Traversa, M
AU  - Traversa M
FAU - Fiore, T
AU  - Fiore T
LA  - ita
PT  - Clinical Trial
PT  - Comparative Study
PT  - Controlled Clinical Trial
PT  - English Abstract
PT  - Journal Article
TT  - Il conteggio post-tetanico dopo tetano a 50 e a 100 Hz nel monitoraggio del 
      blocco neuromuscolare profondo da vecuronio.
PL  - Italy
TA  - Minerva Anestesiol
JT  - Minerva anestesiologica
JID - 0375272
RN  - 7E4PHP5N1D (Vecuronium Bromide)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Electric Stimulation/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Muscle Contraction/*physiology
MH  - *Nerve Block
MH  - Neuromuscular Junction
MH  - *Vecuronium Bromide
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
PST - ppublish
SO  - Minerva Anestesiol. 1994 Jan-Feb;60(1-2):49-53.