PMID- 7911825
OWN - NLM
STAT- MEDLINE
DCOM- 19940719
LR  - 20190830
IS  - 0146-6615 (Print)
IS  - 0146-6615 (Linking)
VI  - 42
IP  - 3
DP  - 1994 Mar
TI  - Molecular epidemiological studies of human herpesvirus 6 in families.
PG  - 224-7
AB  - The mode of transmission of human herpesvirus 6 (HHV-6) was investigated by 
      molecular epidemiological techniques in four families. HHV-6 was isolated from 
      the peripheral blood of seven infants with exanthem subitum, including siblings, 
      and from the saliva of two mothers. These isolates were examined for genetic 
      relatedness by means of restriction enzymes analysis of purified DNA. While the 
      profiles of the digestion patterns differed among families, they were very 
      similar in a particular family. These results may suggest that HHV-6 is 
      transmitted primarily from mother to child.
FAU - Mukai, T
AU  - Mukai T
AD  - Department of Virology, Osaka University, Japan.
FAU - Yamamoto, T
AU  - Yamamoto T
FAU - Kondo, T
AU  - Kondo T
FAU - Kondo, K
AU  - Kondo K
FAU - Okuno, T
AU  - Okuno T
FAU - Kosuge, H
AU  - Kosuge H
FAU - Yamanishi, K
AU  - Yamanishi K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Med Virol
JT  - Journal of medical virology
JID - 7705876
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Adult
MH  - Carrier State/microbiology
MH  - DNA, Viral/analysis
MH  - Exanthema Subitum/microbiology/*transmission
MH  - Female
MH  - Genome, Viral
MH  - Herpesviridae Infections/microbiology/*transmission
MH  - Herpesvirus 6, Human/*genetics/isolation & purification
MH  - Humans
MH  - Infant
MH  - Male
MH  - Mothers
MH  - Nuclear Family
MH  - Polymorphism, Restriction Fragment Length
MH  - Saliva/microbiology
MH  - Viremia/microbiology
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
AID - 10.1002/jmv.1890420303 [doi]
PST - ppublish
SO  - J Med Virol. 1994 Mar;42(3):224-7. doi: 10.1002/jmv.1890420303.