PMID- 7913030
OWN - NLM
STAT- MEDLINE
DCOM- 19940810
LR  - 20061115
IS  - 0889-8529 (Print)
IS  - 0889-8529 (Linking)
VI  - 23
IP  - 1
DP  - 1994 Mar
TI  - Localization and identification of the multiple endocrine neoplasia type 1 
      disease gene.
PG  - 67-79
AB  - The familial and genetic nature of multiple endocrine neoplasia type 1 (MEN 1) 
      syndrome was first pointed out by Wermer in 1954, who suggested that an autosomal 
      dominant gene with high penetrance controls the trait. The clinical picture is 
      variable, depending mainly on which glands are involved and whether the tumors 
      hypersecrete symptom-causing hormones. The most frequent endocrinopathies are 
      hyperparathyroidism, pancreatic-duodenal, and pituitary tumors. Other tumors are 
      also seen more frequently than in the general population, e.g., adrenocortical 
      and thyroid tumors, carcinoids, lipomas, and pinealomas.
FAU - Larsson, C
AU  - Larsson C
AD  - Department of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden.
FAU - Friedman, E
AU  - Friedman E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Endocrinol Metab Clin North Am
JT  - Endocrinology and metabolism clinics of North America
JID - 8800104
RN  - 9002-72-6 (Growth Hormone)
SB  - IM
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 11
MH  - *Genes, Dominant
MH  - Growth Hormone/blood
MH  - Humans
MH  - Multiple Endocrine Neoplasia/blood/*genetics
RF  - 66
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
PST - ppublish
SO  - Endocrinol Metab Clin North Am. 1994 Mar;23(1):67-79.