PMID- 7917044
OWN - NLM
STAT- MEDLINE
DCOM- 19941104
LR  - 20190909
IS  - 0735-7044 (Print)
IS  - 0735-7044 (Linking)
VI  - 108
IP  - 3
DP  - 1994 Jun
TI  - Axon-sparing lesions of the medial nucleus of the amygdala decrease affiliative 
      behaviors in the prairie vole (Microtus ochrogaster): behavioral and anatomical 
      specificity.
PG  - 501-13
AB  - The neural basis of affiliative behavior was examined in the prairie vole, a 
      rodent that exhibits high levels of social contact and paternal behavior. In the 
      first study, the axon-sparing excitotoxin N-methyl-D,L-aspartic acid (NMA) 
      produced lesions in the basolateral nucleus of the amygdala or the corticomedial 
      amygdala. Males with corticomedial lesions showed significantly less contact with 
      a familiar adult female and a pup when compared with males with lesions of the 
      basolateral nucleus or controls. This behavioral change was not associated with 
      changes in exploratory behavior, motor function, performance in an olfactory 
      task, fearfulness, physical well-being, or body temperature. In a second study, 
      NMA lesions restricted to the medial nucleus also decreased paternal behavior. 
      Neurons in the medial nucleus of the amygdala appear to be essential for the 
      normal expression of paternal care in this species.
FAU - Kirkpatrick, B
AU  - Kirkpatrick B
AD  - Maryland Psychiatric Research Center, Department of Psychiatry, University of 
      Maryland School of Medicine, Baltimore 21228.
FAU - Carter, C S
AU  - Carter CS
FAU - Newman, S W
AU  - Newman SW
FAU - Insel, T R
AU  - Insel TR
LA  - eng
GR  - MH00925/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Behav Neurosci
JT  - Behavioral neuroscience
JID - 8302411
SB  - IM
MH  - Amygdala/*physiology
MH  - Animals
MH  - Arousal/physiology
MH  - Arvicolinae
MH  - Axons/*physiology
MH  - Behavior, Animal/*physiology
MH  - Body Temperature Regulation/physiology
MH  - Brain Mapping
MH  - Exploratory Behavior/physiology
MH  - Female
MH  - Male
MH  - Motor Activity/physiology
MH  - Neurons/physiology
MH  - Paternal Behavior
MH  - Sexual Behavior, Animal/physiology
MH  - Smell/physiology
MH  - *Social Behavior
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
AID - 10.1037//0735-7044.108.3.501 [doi]
PST - ppublish
SO  - Behav Neurosci. 1994 Jun;108(3):501-13. doi: 10.1037//0735-7044.108.3.501.