PMID- 7919603
OWN - NLM
STAT- MEDLINE
DCOM- 19941110
LR  - 20221207
IS  - 0267-6591 (Print)
IS  - 0267-6591 (Linking)
VI  - 9
IP  - 2
DP  - 1994 Mar
TI  - Continuous retrograde hypothermic low flow cerebral perfusion during aortic arch 
      surgery.
PG  - 95-9
AB  - Continuous retrograde hypothermic low flow cerebral perfusion (CRCP) with deep 
      hypothermic systemic circulatory arrest (DHSCA) during aortic arch surgery was 
      employed in six patients, aged 21-79 years. From August 1991 to November 1992, 
      five of these patients were operated for ascending and arch aortic dissection 
      type I, and one patient was operated for an aneurysm extending from the ascending 
      aorta into the arch. Cardiopulmonary bypass (CPB) technology included a 
      centrifugal pump and low-dose aprotinin. Venous drainage was established via the 
      superior and inferior caval veins and arterial return via the femoral artery. 
      Prior to CPB, a bypass line connecting the arterial line with the superior vena 
      cava cannula was implemented. Prior to DHSCA, the patients were systemically 
      cooled to a mean nasopharyngeal temperature of 15.2 degrees C. After induction of 
      systemic circulatory arrest, the femoral artery cannula was clamped. Thereafter, 
      the implemented bypass line was opened to achieve reverse flow into the superior 
      vena cava to allow venoarterial perfusion. The perfusate was returned to the CPB 
      circuit through drainage from the inferior caval vein and by aspiration of blood 
      from the opened aortic arch. CRCP flow rate ranged from 250 to 450 ml/min (mean 
      375 ml/min) maintaining an internal jugular vein pressure between 18 and 25 mmHg. 
      The duration of CRCP ranged from 24 to 55 minutes (mean 39 minutes). 
      Postoperatively, one patient died of cardiac failure. The other five patients 
      regained full consciousness without neurological deficits, as defined by the 
      Glasgow coma score, within 48 hours after the operation. Neither did we see other 
      major organ complications.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Everts, P A
AU  - Everts PA
AD  - Department of Extra Corporeal Circulation, Catharina Hospital, Eindhoven, The 
      Netherlands.
FAU - Berreklouw, E
AU  - Berreklouw E
FAU - Box, H A
AU  - Box HA
FAU - Hessels, M M
AU  - Hessels MM
FAU - Schonberger, J P
AU  - Schonberger JP
LA  - eng
PT  - Journal Article
PL  - England
TA  - Perfusion
JT  - Perfusion
JID - 8700166
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aortic Dissection/*surgery
MH  - Aortic Aneurysm/*surgery
MH  - Aortic Aneurysm, Thoracic/surgery
MH  - *Cardiopulmonary Bypass
MH  - *Cerebrovascular Circulation
MH  - Equipment Design
MH  - *Heart Arrest, Induced
MH  - Humans
MH  - Hypothermia, Induced/*methods
MH  - Male
MH  - Middle Aged
MH  - Perfusion/*methods
MH  - Postoperative Complications/mortality
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
AID - 10.1177/026765919400900203 [doi]
PST - ppublish
SO  - Perfusion. 1994 Mar;9(2):95-9. doi: 10.1177/026765919400900203.