PMID- 7924860
OWN - NLM
STAT- MEDLINE
DCOM- 19941102
LR  - 20221207
IS  - 0253-3766 (Print)
IS  - 0253-3766 (Linking)
VI  - 16
IP  - 2
DP  - 1994 Mar
TI  - [Restriction fragment length polymorphism of Bam HI and Rsa I loci in the 
      retinoblastoma gene].
PG  - 115-7
AB  - The retinoblastoma (Rb) gene probe p123 M1.8 and p68 Rs2.0 were used to study the 
      frequencies of the Bam HI and Rsa I restriction fragment length polymorphisms 
      (RFLPs) in the RB gene among the population of Han nationality in Guangdong 
      province. The result showed that the heterozygote rate of the Rsa I locus was 
      only 55.0%, remarkably different from reports in the literature. Linkage study of 
      the Bam HI and the Rsa I RFLPs demonstrated that 10.5% of the Rsa I polymorphic 
      loci were heterozygous for the Bam HI RFLP. Thus the combined use of the two 
      RFLPs can give information for about 65.5% of the population.
FAU - Wei, J
AU  - Wei J
AD  - Sun Yat-sen University of Medical Sciences, Guangzhou.
FAU - Du, C S
AU  - Du CS
LA  - chi
PT  - Clinical Trial
PT  - Journal Article
PL  - China
TA  - Zhonghua Zhong Liu Za Zhi
JT  - Zhonghua zhong liu za zhi [Chinese journal of oncology]
JID - 7910681
SB  - IM
MH  - Asian People
MH  - China
MH  - Female
MH  - Gene Frequency
MH  - *Genes, Retinoblastoma
MH  - Genetic Linkage
MH  - Heterozygote
MH  - Humans
MH  - Male
MH  - *Polymorphism, Restriction Fragment Length
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
PST - ppublish
SO  - Zhonghua Zhong Liu Za Zhi. 1994 Mar;16(2):115-7.