PMID- 7928859
OWN - NLM
STAT- MEDLINE
DCOM- 19941101
LR  - 20171213
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 76
IP  - 6
DP  - 1994 Jun
TI  - Influence of carbohydrate ingestion on fuel substrate turnover and oxidation 
      during prolonged exercise.
PG  - 2364-72
AB  - This study examined effects of ingesting a 10% carbohydrate (CHO) drink (CI) or 
      placebo (PI) at 500 ml/h on total (splanchnic) glucose appearance 
      (endogenous+exogenous; Ra), blood glucose oxidation, and muscle glycogen 
      utilization in 14 male endurance-trained cyclists who rode for 180 min at 70% of 
      maximal O2 uptake after CHO loading [starting muscle glycogen 203 +/- 7 (SE) 
      mmol/kg wet wt]. Total CHO oxidation was similar in CI and PI, but Ra increased 
      significantly during the trial in both groups with CI reaching a plateau after 75 
      min. Ra was significantly greater in CI than in PI at the end of exercise. Blood 
      glucose oxidation also increased significantly during the trial to a plateau in 
      CI and was significantly higher in CI than in PI at the end of exercise. However, 
      mean endogenous Ra was significantly lower in CI than in PI throughout exercise, 
      as was oxidation of endogenous blood glucose, which remained almost constant in 
      CI and reached 43 +/- 8 and 73 +/- 13 mumol.min-1.kg fat-free mass-1 in CI and 
      PI, respectively, at the end of exercise. At 0.83 g/min of CHO ingestion, 0.77 
      +/- 0.03 g/min was oxidized. Muscle glycogen utilization was identical in both 
      groups and was higher during the 1st h of exercise.(ABSTRACT TRUNCATED AT 250 
      WORDS)
FAU - Bosch, A N
AU  - Bosch AN
AD  - Department of Physiology, University of Cape Town Medical School, Observatory, 
      South Africa.
FAU - Dennis, S C
AU  - Dennis SC
FAU - Noakes, T D
AU  - Noakes TD
LA  - eng
PT  - Clinical Trial
PT  - Controlled Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Fats)
RN  - 0 (Lactates)
RN  - 142M471B3J (Carbon Dioxide)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 9005-79-2 (Glycogen)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Adult
MH  - Bicycling
MH  - Blood Glucose/metabolism
MH  - Carbon Dioxide/metabolism
MH  - Dietary Carbohydrates/*pharmacology
MH  - Energy Metabolism/*physiology
MH  - Exercise/*physiology
MH  - Fats/metabolism
MH  - Glucose/metabolism
MH  - Glycogen/metabolism
MH  - Humans
MH  - Kinetics
MH  - Lactates/blood
MH  - Lactic Acid
MH  - Liver/metabolism
MH  - Male
MH  - Muscles/metabolism
MH  - Oxidation-Reduction
MH  - Oxygen Consumption/physiology
MH  - Physical Endurance/*physiology
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
AID - 10.1152/jappl.1994.76.6.2364 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 1994 Jun;76(6):2364-72. doi: 10.1152/jappl.1994.76.6.2364.