PMID- 7931725
OWN - NLM
STAT- MEDLINE
DCOM- 19941028
LR  - 20190830
IS  - 0301-4800 (Print)
IS  - 0301-4800 (Linking)
VI  - 40
IP  - 2
DP  - 1994 Apr
TI  - Effects of fructooligosaccharides on the absorption of magnesium in the 
      magnesium-deficient rat model.
PG  - 171-80
AB  - Magnesium (Mg) is an essential dietary element that plays important roles, acting 
      as a cofactor of many enzymes. Rats fed a Mg-deficient diet have been reported to 
      exhibit auricular and facial peripheral hyperemia and hemorrhage. Moreover, 
      increased intake of calcium (Ca) or phosphorus (P) has been reported to impair 
      apparent absorption of Mg. We tried to induce such typical inflammation in 
      Mg-deficient rats by feeding low-Mg, high-Ca, and high-P diets. Increasing 
      concentrations of Ca or P in the experimental diets significantly decreased the 
      apparent absorption of Mg. And all rats fed the low-Mg (0.25 mg/g diet), high-Ca 
      (10.4 mg/g diet), and high-P (12.0 mg/g diet) diet exhibited auricular and facial 
      peripheral-hyperemia and hemorrhage. Then, we used the low-Mg, high-Ca, and 
      high-P diet to investigate the effects of the fructooligosaccharides (FO) on 
      absorption of Mg and skin inflammation. In the rats fed FO-containing (1 or 5%) 
      diet, apparent absorption of Mg was significantly increased as compared with that 
      of the control (FO 0%) group. In the rats fed a 5% FO-containing diet and 
      sufficient Mg (0.50 mg/g), auricular and facial peripheral hyperemia and 
      hemorrhage were significantly reduced. We concluded that FO increased the Mg 
      absorption in rats fed a low-Mg, high-Ca, and high-P diet. Moreover, FO reduced 
      inflammation in Mg-deficient rats, such as peripheral hyperemia and hemorrhage.
FAU - Ohta, A
AU  - Ohta A
AD  - Bio Science Laboratories, Meiji Seika Kaisha, Ltd., Sakado, Japan.
FAU - Baba, S
AU  - Baba S
FAU - Takizawa, T
AU  - Takizawa T
FAU - Adachi, T
AU  - Adachi T
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - J Nutr Sci Vitaminol (Tokyo)
JT  - Journal of nutritional science and vitaminology
JID - 0402640
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Oligosaccharides)
RN  - 13133-07-8 (fungitetraose)
RN  - 27YLU75U4W (Phosphorus)
RN  - I38ZP9992A (Magnesium)
RN  - SY7Q814VUP (Calcium)
SB  - IM
MH  - Animals
MH  - Body Weight
MH  - Calcium/administration & dosage/metabolism
MH  - Diet
MH  - Dietary Carbohydrates/administration & dosage/*pharmacology
MH  - *Disease Models, Animal
MH  - Eating
MH  - Intestinal Absorption/*drug effects
MH  - Magnesium/administration & dosage/*metabolism
MH  - Magnesium Deficiency/*metabolism
MH  - Male
MH  - Oligosaccharides/administration & dosage/*pharmacology
MH  - Phosphorus/administration & dosage/metabolism
MH  - Rats
MH  - Rats, Sprague-Dawley
EDAT- 1994/04/01 00:00
MHDA- 1994/04/01 00:01
CRDT- 1994/04/01 00:00
PHST- 1994/04/01 00:00 [pubmed]
PHST- 1994/04/01 00:01 [medline]
PHST- 1994/04/01 00:00 [entrez]
AID - 10.3177/jnsv.40.171 [doi]
PST - ppublish
SO  - J Nutr Sci Vitaminol (Tokyo). 1994 Apr;40(2):171-80. doi: 10.3177/jnsv.40.171.