PMID- 7942485
OWN - NLM
STAT- MEDLINE
DCOM- 19941118
LR  - 20190626
IS  - 0002-8703 (Print)
IS  - 0002-8703 (Linking)
VI  - 128
IP  - 5
DP  - 1994 Nov
TI  - Arrhythmias in mitral valve prolapse: relation to anterior mitral leaflet 
      thickening, clinical variables, and color Doppler echocardiographic parameters.
PG  - 919-27
AB  - Atrial and ventricular arrhythmias have been reported with variable incidence in 
      symptomatic patients with mitral valve prolapse (MVP). The role of clinical and 
      echocardiographic parameters as predictors for arrhythmias still needs to be 
      clarified. One hundred nineteen consecutive patients (56 women and 63 men, mean 
      age 40 +/- 17 years) with echocardiographically diagnosed MVP were examined. A 
      complete echocardiographic study (M-mode, two-dimensional, and Doppler) and 
      24-hour electrocardiographic monitoring were performed in all patients. Complex 
      atrial arrhythmias (CAAs) included atrial couplets, atrial tachycardia, and 
      paroxysmal or sustained atrial flutter or fibrillation. Complex ventricular 
      arrhythmias (CVAs) included multiform ventricular premature contractions (VPCs), 
      VPC couplets, and runs of three or more sequential VPCs (salvos of ventricular 
      tachycardia). The relation between complex arrhythmias and clinical parameters 
      (age and gender) and echocardiographic parameters (left atrial and left 
      ventricular dimensions, anterior mitral leaflet thickness [AMLT], and presence 
      and severity of mitral regurgitation) was evaluated by multiple logistic 
      regression analysis. CAA were present in 14% of patients and CVA in 30%. 
      According to multiple logistic modeling, CAA correlated separately in the 
      univariate analysis with age, presence of MR, and left ventricular and left 
      atrial diameters; age was the only independent predictor (p < 0.001). CVA, in the 
      univariate analysis, correlated with age, female gender, left ventricular 
      end-diastolic diameter, and AMLT; only female gender and AMLT were independent 
      predictors in the multivariate analysis (p < 0.01). The incidence of mitral 
      regurgitation (59%) was higher than expected in a general population of MVP 
      patients.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Zuppiroli, A
AU  - Zuppiroli A
AD  - Servizio di Cardiologia S. Luca, Ospedale di Careggi, USL 10/D, Firenze, Italy.
FAU - Mori, F
AU  - Mori F
FAU - Favilli, S
AU  - Favilli S
FAU - Barchielli, A
AU  - Barchielli A
FAU - Corti, G
AU  - Corti G
FAU - Montereggi, A
AU  - Montereggi A
FAU - Dolara, A
AU  - Dolara A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Arrhythmias, Cardiac/diagnosis/epidemiology/*etiology
MH  - *Echocardiography, Doppler, Color
MH  - Electrocardiography, Ambulatory
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Logistic Models
MH  - Male
MH  - Mitral Valve/diagnostic imaging
MH  - Mitral Valve Insufficiency/complications/epidemiology
MH  - Mitral Valve Prolapse/*complications/diagnostic imaging
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Risk Factors
MH  - Selection Bias
MH  - Sex Factors
EDAT- 1994/11/01 00:00
MHDA- 1994/11/01 00:01
CRDT- 1994/11/01 00:00
PHST- 1994/11/01 00:00 [pubmed]
PHST- 1994/11/01 00:01 [medline]
PHST- 1994/11/01 00:00 [entrez]
AID - 0002-8703(94)90590-8 [pii]
AID - 10.1016/0002-8703(94)90590-8 [doi]
PST - ppublish
SO  - Am Heart J. 1994 Nov;128(5):919-27. doi: 10.1016/0002-8703(94)90590-8.