PMID- 7950905
OWN - NLM
STAT- MEDLINE
DCOM- 19941201
LR  - 20031114
IS  - 0956-523X (Print)
IS  - 0956-523X (Linking)
VI  - 4
IP  - 2
DP  - 1994 Jun
TI  - Cell- and stage-specific expression of basic FGF in the developing rat gonads.
PG  - 77-81
AB  - In order to clarify the participation of basic fibroblast growth factor (bFGF) in 
      rat gonadal differentiation and development, immunohistochemical localizations of 
      bFGF were chronologically studied in Sprague-Dawley rat gonads from gestational 
      day (GD) 13 to postnatal day (PD) 21 by using avidin-biotin complex technique. 
      Immunohistochemical reactivity to bFGF antibody was positive in the germ cells. 
      Slight or moderate immunostaining was seen in male germ cells from GD 18 to PD 5, 
      and in female germ cells from PD 5 to 21. Leydig/interstitial cells in male 
      gonads were slightly or moderately stained from GD 16 to PD 21. On the other 
      hand, other types of gonadal cells were not stained during the perinatal period. 
      These results indicate that bFGF shows discrete cell- and stage-specific patterns 
      of expression in gonads during the perinatal period and is likely to participate 
      in control of gonadal development in rats.
FAU - Koike, S
AU  - Koike S
AD  - Department of Regulation Biology, Faculty of Science, Saitama University, Japan.
FAU - Noumura, T
AU  - Noumura T
LA  - eng
PT  - Journal Article
PL  - Scotland
TA  - Growth Regul
JT  - Growth regulation
JID - 9106990
RN  - 103107-01-3 (Fibroblast Growth Factor 2)
SB  - IM
MH  - Animals
MH  - Cell Differentiation
MH  - Female
MH  - Fibroblast Growth Factor 2/*analysis
MH  - Immunohistochemistry
MH  - Leydig Cells/chemistry/cytology
MH  - Male
MH  - Ovary/*chemistry/cytology/*growth & development
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Testis/*chemistry/cytology/*growth & development
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
PST - ppublish
SO  - Growth Regul. 1994 Jun;4(2):77-81.