PMID- 795259
OWN - NLM
STAT- MEDLINE
DCOM- 19770226
LR  - 20190812
IS  - 0001-6322 (Print)
IS  - 0001-6322 (Linking)
VI  - 36
IP  - 3
DP  - 1976 Nov 15
TI  - Immunoperoxidase staining of simple nuclear bodies in sclerosing panencephalitis 
      (SSPE) by antiserum to Measles nucleocapsids.
PG  - 259-67
AB  - Nuclear bodies have been found with great consistency in brain tissue from 
      patients with subacute sclerosing panencephalitis (SSPE). There has been 
      controversy as to the significance of these structures and their relationship, if 
      any, to the disease. In this study, a non-productive, cell-associated strain of 
      SSPE measles virus grown in tissue culture on Vero cells showed the continued 
      presence of nuclear bodies, frequently in close association with the continued 
      presence of nuclear bodies, frequently in close association with the SSPE measles 
      virus nucleocapsids. Immunoperoxidase (I-P) staining with specific antiserum 
      against measles virus nucleocapsids was done. The resultant positive labeling of 
      the nuclear bodies demonstrates that they contain measles virus antigen and 
      suggests that the nuclear bodies play a role in the development of the measles 
      virus nucleocapsids of SSPE.
FAU - Brown, H R
AU  - Brown HR
FAU - Thormar, H
AU  - Thormar H
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Acta Neuropathol
JT  - Acta neuropathologica
JID - 0412041
RN  - 0 (Antigens, Viral)
SB  - IM
MH  - Antigens, Viral/analysis
MH  - Cell Line
MH  - Cell Nucleus/*microbiology
MH  - Humans
MH  - Immunoenzyme Techniques
MH  - *Inclusion Bodies, Viral
MH  - *Measles virus
MH  - Microscopy, Electron
MH  - Subacute Sclerosing Panencephalitis/*microbiology
EDAT- 1976/11/15 00:00
MHDA- 1976/11/15 00:01
CRDT- 1976/11/15 00:00
PHST- 1976/11/15 00:00 [pubmed]
PHST- 1976/11/15 00:01 [medline]
PHST- 1976/11/15 00:00 [entrez]
AID - 10.1007/BF00685370 [doi]
PST - ppublish
SO  - Acta Neuropathol. 1976 Nov 15;36(3):259-67. doi: 10.1007/BF00685370.