PMID- 7955241
OWN - NLM
STAT- MEDLINE
DCOM- 19941209
LR  - 20101118
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 90
IP  - 5 Pt 2
DP  - 1994 Nov
TI  - Two decades of coronary artery bypass graft surgery in young adults.
PG  - II133-9
AB  - Between January 1970 and December 1991, 201 patients < or = 40 years of age 
      underwent coronary artery bypass graft surgery (CABG). Group 1 (1970 to 1980, n = 
      119) and group 2 (1981 to 1991, n = 82) corresponded to the eras before and after 
      the onset of percutaneous transluminal coronary angioplasty (PTCA), respectively, 
      and were analyzed for trends in patient profile, treatment, and risk factors for 
      coronary artery disease (CAD): smoking, hypertension, hypercholesterolemia, 
      diabetes, and family history. Mean age at operation was similar in the groups (1, 
      37 +/- 3.4 years; 2, 36 +/- 3.1 years). Women made up 18% of group 1 and 27% of 
      group 2 (P = .048). Risk factor profile differed in the two groups: group 1 had 
      more smokers (80%) than group 2 (68%) (P = .085), fewer patients with 
      hypercholesterolemia (1, 37%; 2, 52%; P = .065), and significantly fewer 
      diabetics (1, 10%; 2, 25%; P < .043). Mean preoperative New York Heart 
      Association (NYHA) class was 3.2 in group 1 and 3.0 in group 2. The distributions 
      of single-, double-, and triple-vessel CAD were similar in the groups. 
      Preoperative myocardial infarction occurred in 55% of group 1 versus 61% in group 
      2 (P = NS). No group 1 patient received PTCA before CABG, but PTCA was performed 
      in 15 group 2 patients. Left internal mammary artery grafts were used in 4% of 
      group 1 and 57% of group 2 patients. CABG operative mortality was 7.0% in group 1 
      and 1.2% in group 2.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Zehr, K J
AU  - Zehr KJ
AD  - Division of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD 21287.
FAU - Lee, P C
AU  - Lee PC
FAU - Poston, R S
AU  - Poston RS
FAU - Gillinov, A M
AU  - Gillinov AM
FAU - Greene, P S
AU  - Greene PS
FAU - Cameron, D E
AU  - Cameron DE
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Controlled Clinical Trial
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
SB  - IM
MH  - Actuarial Analysis
MH  - Adult
MH  - Angioplasty, Balloon, Coronary
MH  - Coronary Artery Bypass/*statistics & numerical data
MH  - Coronary Disease/epidemiology/*surgery
MH  - Disease-Free Survival
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Multivariate Analysis
MH  - Postoperative Complications/epidemiology
MH  - Prevalence
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Survival Rate
MH  - Time Factors
EDAT- 1994/11/01 00:00
MHDA- 1994/11/01 00:01
CRDT- 1994/11/01 00:00
PHST- 1994/11/01 00:00 [pubmed]
PHST- 1994/11/01 00:01 [medline]
PHST- 1994/11/01 00:00 [entrez]
PST - ppublish
SO  - Circulation. 1994 Nov;90(5 Pt 2):II133-9.