PMID- 7957139 OWN - NLM STAT- MEDLINE DCOM- 19941125 LR - 20190830 IS - 0301-5548 (Print) IS - 0301-5548 (Linking) VI - 68 IP - 6 DP - 1994 TI - Muscle glycogen repletion and pre-exercise glycogen content: effect of carbohydrate loading in rats previously fed a high fat diet. PG - 483-8 AB - We have recently reported that rates of muscle glycogen repletion during the early period of recovery were increased by carbohydrate (CHO) loading in rats previously fed a high fat diet. However, the reason for this remained unanswered. The purpose of this study was to examine whether an increase of glycogen utilization due to an elevated pre-exercise glycogen store would enhance rates of glycogen repletion in muscle. Despite an equal degree of glycogen depletion, the rates of glycogen repletion of soleus, red and white gastrocnemius muscles by postexercise administration of glucose (3.0 g.kg-1 body mass) and citrate (0.5 g.kg-1 body mass) were faster in the CHO loaded (3 days) rats than in the nonloaded rats, as a result of elevated pre-exercise glycogen content and consequently the greater glycogen utilization. The higher rate of muscle glycogen repletion may in part be explained by increased postexercise glycogen synthase activity. FAU - Saitoh, S AU - Saitoh S AD - Laboratory of Biochemistry of Exercise and Nutrition, University of Tsukuba, Ibaraki, Japan. FAU - Tasaki, Y AU - Tasaki Y FAU - Tagami, K AU - Tagami K FAU - Suzuki, M AU - Suzuki M LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Germany TA - Eur J Appl Physiol Occup Physiol JT - European journal of applied physiology and occupational physiology JID - 0410266 RN - 0 (Dietary Carbohydrates) RN - 0 (Dietary Fats) RN - 0 (Insulin) RN - 0 (Liver Glycogen) RN - 0 (Thyroid Hormones) RN - 9005-79-2 (Glycogen) RN - EC 2.4.1.11 (Glycogen Synthase) SB - IM MH - Animal Feed MH - Animals MH - Blood Chemical Analysis MH - Body Weight MH - Dietary Carbohydrates/*administration & dosage MH - Dietary Fats/*administration & dosage MH - Glycogen/*metabolism MH - Glycogen Synthase/metabolism MH - Insulin/blood MH - Liver Glycogen/metabolism MH - Male MH - Muscle, Skeletal/*metabolism MH - Physical Exertion/*physiology MH - Rats MH - Rats, Sprague-Dawley MH - Thyroid Hormones/blood EDAT- 1994/01/01 00:00 MHDA- 1994/01/01 00:01 CRDT- 1994/01/01 00:00 PHST- 1994/01/01 00:00 [pubmed] PHST- 1994/01/01 00:01 [medline] PHST- 1994/01/01 00:00 [entrez] AID - 10.1007/BF00599517 [doi] PST - ppublish SO - Eur J Appl Physiol Occup Physiol. 1994;68(6):483-8. doi: 10.1007/BF00599517.