PMID- 7970236 OWN - NLM STAT- MEDLINE DCOM- 19941229 LR - 20190701 IS - 0304-3940 (Print) IS - 0304-3940 (Linking) VI - 176 IP - 1 DP - 1994 Jul 18 TI - Effective induction of pregnancy block by electrical stimulation of the mouse accessory olfactory bulb coincident with prolactin surges. PG - 5-8 AB - Electrical stimulation (0.33 Hz, 0.2 mA) applied bilaterally to the accessory olfactory bulb (AOB) of newly mated female mice revealed that stimulation for 4 h was sufficient to produce pregnancy block providing stimulation is given for two separate 2-h periods coincident with prolactin surges. Stimulation for two 1-h periods coincident with prolactin surges or two 2-h periods between prolactin surges was without effect. These results indicate that electrical stimulation of the AOB can faithfully reproduce pheromone-induced pregnancy block and support the view that prolactin is the hormone mainly responsible for the olfactory block to pregnancy. FAU - Li, C S AU - Li CS AD - Department of Physiology, Kochi Medical School, Japan. FAU - Kaba, H AU - Kaba H FAU - Seto, K AU - Seto K LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Ireland TA - Neurosci Lett JT - Neuroscience letters JID - 7600130 RN - 9002-62-4 (Prolactin) SB - IM MH - Animals MH - Circadian Rhythm MH - *Electric Stimulation MH - Estrus MH - Female MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Olfactory Bulb/metabolism/*physiology MH - Physical Stimulation MH - Pregnancy MH - *Pregnancy, Animal MH - Prolactin/*metabolism EDAT- 1994/07/18 00:00 MHDA- 1994/07/18 00:01 CRDT- 1994/07/18 00:00 PHST- 1994/07/18 00:00 [pubmed] PHST- 1994/07/18 00:01 [medline] PHST- 1994/07/18 00:00 [entrez] AID - 0304-3940(94)90857-5 [pii] AID - 10.1016/0304-3940(94)90857-5 [doi] PST - ppublish SO - Neurosci Lett. 1994 Jul 18;176(1):5-8. doi: 10.1016/0304-3940(94)90857-5.