PMID- 7982290
OWN - NLM
STAT- MEDLINE
DCOM- 19950103
LR  - 20190825
IS  - 0305-1870 (Print)
IS  - 0305-1870 (Linking)
VI  - 21
IP  - 7
DP  - 1994 Jul
TI  - Blood volume measurements in the neonatal lamb: validation of a method using 
      [51Cr]-labelled red cells.
PG  - 577-81
AB  - 1. The reproducibility of blood volume measurements, using [51Cr]-labelled red 
      blood cells (RBC) was tested in three lambs, 79-89 days of age, and the accuracy 
      was tested in eight lambs, 83 +/- 0.4 days of age, in which blood volume was 
      measured simultaneously by [51Cr]-RBC and [125I]-gamma globulin plus haematocrit 
      (hct). 2. The blood volumes (mean +/- s.e.) of the three lambs, on four 
      occasions, were 64.5 +/- 2.5, 68.8 +/- 2.9 and 63.9 +/- 3.7 mL/kg, respectively, 
      and the coefficients of variation were 7.8, 8.6 and 11.6%, respectively. 3. The 
      mean blood volume of eight lambs was 60.9 +/- 3.3 mL/kg by [51Cr]-RBC, and 60.8 
      +/- 2.4 mL/kg from plasma volume and hct. These were not statistically different. 
      4. Arterial hct was 31.2 +/- 0.5%, which was not statistically different from the 
      whole body hct of 31.2 +/- 2.6%. 5. It is concluded that [51Cr]-RBC can be used 
      to measure accurate and reproducible blood volumes in lambs.
FAU - Moritz, K M
AU  - Moritz KM
AD  - Howard Florey Institute of Experimental Physiology and Medicine, University of 
      Melbourne, Parkville, Victoria, Australia.
FAU - Potocnik, S J
AU  - Potocnik SJ
FAU - Tangalakis, K
AU  - Tangalakis K
FAU - Wintour, E M
AU  - Wintour EM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Australia
TA  - Clin Exp Pharmacol Physiol
JT  - Clinical and experimental pharmacology & physiology
JID - 0425076
RN  - 0 (Chromium Radioisotopes)
RN  - 0 (Hemoglobins)
RN  - 0 (Iodine Radioisotopes)
RN  - 9034-51-9 (Hemoglobin A)
RN  - 9041-75-2 (hemoglobin B)
SB  - IM
MH  - Animals
MH  - Animals, Newborn/*physiology
MH  - Blood Volume Determination/*methods
MH  - Chromium Radioisotopes
MH  - Erythrocytes/*physiology
MH  - Female
MH  - Hematocrit
MH  - Hemoglobin A/metabolism
MH  - Hemoglobins/metabolism
MH  - Iodine Radioisotopes
MH  - Male
MH  - Plasma Volume/physiology
MH  - Sheep
EDAT- 1994/07/01 00:00
MHDA- 1994/07/01 00:01
CRDT- 1994/07/01 00:00
PHST- 1994/07/01 00:00 [pubmed]
PHST- 1994/07/01 00:01 [medline]
PHST- 1994/07/01 00:00 [entrez]
AID - 10.1111/j.1440-1681.1994.tb02557.x [doi]
PST - ppublish
SO  - Clin Exp Pharmacol Physiol. 1994 Jul;21(7):577-81. doi: 
      10.1111/j.1440-1681.1994.tb02557.x.