PMID- 7987795
OWN - NLM
STAT- MEDLINE
DCOM- 19950110
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 78
IP  - 1
DP  - 1994 Nov
TI  - Appreciation of the significance of cytogenetic and FISH analysis of bone marrow 
      in clinical oncology.
PG  - 10-4
AB  - Due to some empiric reasons, bone marrow (BM) has never been emphasized and 
      appreciated as a valuable alternative source for metaphases of tumor nature. In 
      the present study, we report the cytogenetic and fluorescence in situ 
      hybridization (FISH) studies of BM in 172 patients with various tumors. Our 
      results indicate that cytogenetic and FISH analyses of BM provide a valuable 
      biologic approach concerning the diagnosis of tumors, evaluation of metastasis, 
      and assessment of secondary hematologic malignancies. Thus, we suggest strongly 
      that these studies become a standard part of clinical pathologic investigations 
      in dealing with clinical oncology.
FAU - Chen, Z
AU  - Chen Z
AD  - Genetrix, Inc., Scottsdale, Arizona.
FAU - Morgan, R
AU  - Morgan R
FAU - Stone, J F
AU  - Stone JF
FAU - Sandberg, A A
AU  - Sandberg AA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Bone Marrow/*pathology
MH  - *Chromosome Aberrations
MH  - Female
MH  - Hematologic Diseases/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Neoplasm Metastasis/genetics
MH  - Neoplasms/*genetics/pathology
EDAT- 1994/11/01 00:00
MHDA- 1994/11/01 00:01
CRDT- 1994/11/01 00:00
PHST- 1994/11/01 00:00 [pubmed]
PHST- 1994/11/01 00:01 [medline]
PHST- 1994/11/01 00:00 [entrez]
AID - 0165-4608(94)90039-6 [pii]
AID - 10.1016/0165-4608(94)90039-6 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1994 Nov;78(1):10-4. doi: 10.1016/0165-4608(94)90039-6.