PMID- 7987798 OWN - NLM STAT- MEDLINE DCOM- 19950110 LR - 20190816 IS - 0165-4608 (Print) IS - 0165-4608 (Linking) VI - 78 IP - 1 DP - 1994 Nov TI - Reassessment of an apparent t(12;17)(p11;p11) as an unbalanced t(17;21)(p11;q11) in a case of B-cell chronic lymphocytic leukemia by fluorescence in situ hybridization. PG - 108-11 AB - We report a published case of chronic lymphocytic leukemia (CLL) in which conventional cytogenetic analysis supported the presence of an unbalanced t(12;17)(p11;p11). However, fluorescence in situ hybridization (FISH) analysis, with specific DNA libraries from chromosomes 17 and 21 (chromosome painting), demonstrated that the translocation was actually an unbalanced t(17;21)(p11;q11). FAU - Flactif, M AU - Flactif M AD - Laboratoire de Genetique Humaine, Faculte de Medicine, C.H.R.U., Lille, France. FAU - Lai, J L AU - Lai JL FAU - Fenaux, P AU - Fenaux P LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Cancer Genet Cytogenet JT - Cancer genetics and cytogenetics JID - 7909240 SB - IM MH - Aged MH - *Chromosomes, Human, Pair 12 MH - *Chromosomes, Human, Pair 17 MH - *Chromosomes, Human, Pair 21 MH - Female MH - Humans MH - In Situ Hybridization, Fluorescence MH - Karyotyping MH - Leukemia, Lymphocytic, Chronic, B-Cell/*genetics MH - *Translocation, Genetic EDAT- 1994/11/01 00:00 MHDA- 1994/11/01 00:01 CRDT- 1994/11/01 00:00 PHST- 1994/11/01 00:00 [pubmed] PHST- 1994/11/01 00:01 [medline] PHST- 1994/11/01 00:00 [entrez] AID - 0165-4608(94)90057-4 [pii] AID - 10.1016/0165-4608(94)90057-4 [doi] PST - ppublish SO - Cancer Genet Cytogenet. 1994 Nov;78(1):108-11. doi: 10.1016/0165-4608(94)90057-4.