PMID- 7994747 OWN - NLM STAT- MEDLINE DCOM- 19950118 LR - 20121115 IS - 0098-6569 (Print) IS - 0098-6569 (Linking) VI - Suppl 2 DP - 1994 TI - Percutaneous transvenous mitral commissurotomy using Inoue catheter in juvenile rheumatic mitral stenosis. PG - 82-6 AB - Percutaneous transvenous mitral commissurotomy (PTMC) using Inoue balloon was performed in 270 patients with rheumatic mitral stenosis. Of these 81 (27%), 48 males and 33 females, had juvenile mitral stenosis (age < 20 years, range 9-20 years mean 14 +/- 5). All patients were symptomatic (New York Heart Association [NYHA] class III in 61 patients and class IV in 20 patients). Following PTMC, the mitral valve area (MVA) increased from 0.8 +/- 0.4 to 2.2 +/- 0.5 cm2 (P < 0.001) and the cardiac index increased from 2.4 +/- 0.8 to 3.0 +/- 0.8 L/min/m2 (P < 0.001). Mean transmitral gradients decreased from 24 +/- 8 to 4 +/- 3 mm Hg (P < 0.001). Three (4%) patients had an increase in mitral regurgitation by 1 grade (grade 2/4); however, none required surgery. Significant left to right atrial shunt (Qp/Qs > 1.3: 1) on oximetry was detected in 8 (10%) patients. Overall results were compared to those with adult subgroup of patients with rheumatic mitral stenosis (n = 189, 100 females and 89 males), who underwent PTMC simultaneously. Their age ranged from 21 to 44 years (mean 32 +/- 11 years). The percentage increase in MVA was higher in juvenile as compared to adult patients (172 +/- 61 vs. 154 +/- 69, respectively, P < 0.01). A larger final MVA was achieved in the juvenile group (2.2 +/- 0.5 vs. 1.9 +/- 0.3 cm2, P < 0.05). However, the incidence of increase in mitral regurgitation by 1 grade was similar in two groups (6% vs. 4%, P = NS).(ABSTRACT TRUNCATED AT 250 WORDS) FAU - Bahl, V K AU - Bahl VK AD - Department of Cardiology, All India Institute of Medical Sciences, New Delhi. FAU - Chandra, S AU - Chandra S FAU - Kothari, S S AU - Kothari SS FAU - Talwar, K K AU - Talwar KK FAU - Sharma, S AU - Sharma S FAU - Kaul, U AU - Kaul U FAU - Rajani, M AU - Rajani M FAU - Wasir, H S AU - Wasir HS LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - Cathet Cardiovasc Diagn JT - Catheterization and cardiovascular diagnosis JID - 7508512 SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - *Catheterization/adverse effects/instrumentation/methods MH - Child MH - Female MH - Fibrosis MH - Follow-Up Studies MH - Humans MH - Male MH - Mitral Valve/pathology MH - Mitral Valve Stenosis/etiology/pathology/*therapy MH - Prognosis MH - Rheumatic Heart Disease/*complications/therapy EDAT- 1994/01/01 00:00 MHDA- 1994/01/01 00:01 CRDT- 1994/01/01 00:00 PHST- 1994/01/01 00:00 [pubmed] PHST- 1994/01/01 00:01 [medline] PHST- 1994/01/01 00:00 [entrez] PST - ppublish SO - Cathet Cardiovasc Diagn. 1994;Suppl 2:82-6.