PMID- 7995396
OWN - NLM
STAT- MEDLINE
DCOM- 19950119
LR  - 20221207
IS  - 0903-1936 (Print)
IS  - 0903-1936 (Linking)
VI  - 7
IP  - 9
DP  - 1994 Sep
TI  - The ageing of lung function: cross-sectional and longitudinal studies of an Inuit 
      community.
PG  - 1653-9
AB  - Three surveys (1969/1970, 1979/1980 and 1989/1990) have examined the impact of 
      acculturation to a sedentary lifestyle on the pulmonary function of a circumpolar 
      native Inuit community. The sample comprised more than 50% of those aged 20-60 
      yrs, most recently 119 males and 92 females. Forced vital capacity (FVC), forced 
      expiratory volume in one second (FEV1) and maximal mid-expiratory flow (MMEF) 
      were measured by standard spirometric techniques, and information was obtained on 
      smoking habits and health. Multiple regression equations showed that lung 
      function was affected by height and age, but usually not by age squared. 
      Cross-sectional age coefficients for FVC and FEV1 increased over the period 
      1969/1970 to 1989/1990. Parallel longitudinal trends were seen in FEV1 (males 
      only). Multiple analysis of variance (MANOVA) showed age-decade*cohort effects 
      for FVC and FEV1 (males but not females). Almost all of the population now smoke 
      (mean +/- SD males 13 +/- 8 cigarettes.day-1; females 11 +/- 7 cigarettes.day-1). 
      However, smoking bears little relationship to lung function perhaps due to 
      limited variance in consumption. About a third of the community have 
      physician-diagnosed and/or radiographically visible chest disease, but with 
      little effect upon pulmonary function. We conclude that an apparent secular trend 
      to a faster ageing of lung function in men is not explained by disease or 
      domestic air pollution. Possible factors include increased lung volumes in young 
      adults, greater pack-years of cigarette exposure, nonspecific respiratory 
      disease, increased inspiration of cold air or altered chest mechanics due to 
      operation of high-speed snowmobiles, and loss of physical fitness.
FAU - Rode, A
AU  - Rode A
AD  - School of Physical & Health Education, Faculty of Medicine, University of 
      Toronto, Canada.
FAU - Shephard, R J
AU  - Shephard RJ
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Eur Respir J
JT  - The European respiratory journal
JID - 8803460
SB  - IM
MH  - Acculturation
MH  - Adult
MH  - Aging/*physiology
MH  - Arctic Regions
MH  - Canada
MH  - Cold Climate
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - *Inuit
MH  - Life Style
MH  - Longitudinal Studies
MH  - Lung/*physiology
MH  - Male
MH  - Middle Aged
MH  - Regression Analysis
MH  - Respiratory Function Tests
MH  - Respiratory Tract Diseases/ethnology
MH  - Smoking/physiopathology
EDAT- 1994/09/01 00:00
MHDA- 1994/09/01 00:01
CRDT- 1994/09/01 00:00
PHST- 1994/09/01 00:00 [pubmed]
PHST- 1994/09/01 00:01 [medline]
PHST- 1994/09/01 00:00 [entrez]
AID - 10.1183/09031936.94.07091653 [doi]
PST - ppublish
SO  - Eur Respir J. 1994 Sep;7(9):1653-9. doi: 10.1183/09031936.94.07091653.