PMID- 8000059
OWN - NLM
STAT- MEDLINE
DCOM- 19950124
LR  - 20181130
IS  - 1001-9294 (Print)
IS  - 1001-9294 (Linking)
VI  - 9
IP  - 2
DP  - 1994 Jun
TI  - A new functional classification of stomach cancer and its pathobiological and 
      clinical significance.
PG  - 119-24
AB  - The functional differentiations of stomach cancer specimens from 121 patients 
      were investigated by enzyme-, mucin-, affinity- and immunohistochemical methods, 
      and the stomach cancers were divided into five functionally differentiated types: 
      1) Absorptive Function Differentiation Type (AFDT), 19.8%; 2) Mucin Secreting 
      Function Differentiation Type (MSFDT), 24.0%; 3) Absorptive and Mucin-Producing 
      Function Differentiation Type (AMPFDT), 47.1%; 4) Special Function 
      Differentiation Type (SFDT), 0.8%; and 5) Non-Function Differentiation Type 
      (NFDT), 8.3%. The results indicate that stomach cancer tissues of the same 
      histological type often display differing functional differentiation, and these 
      functionally differentiated types have different invasive and metastatic 
      characteristics. In addition, the functionally differentiated types have 
      particular organic affinities of metastasis and different clinical prognoses. 
      This study suggests that this new functional classification may supplement 
      histological classification. The mechanisms of liver and ovary metastases of 
      stomach cancer are also discussed.
FAU - Xin, Y
AU  - Xin Y
AD  - Cancer Institute, China Medical University, Shenyang.
FAU - Zhao, F
AU  - Zhao F
FAU - Gong, W
AU  - Gong W
FAU - Wang, Y
AU  - Wang Y
FAU - Zhang, Y
AU  - Zhang Y
FAU - Yan, R
AU  - Yan R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Chin Med Sci J
JT  - Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih
JID - 9112559
RN  - 0 (Laminin)
RN  - 0 (Mucins)
RN  - 0 (Receptors, Estrogen)
SB  - IM
MH  - Adenocarcinoma/*classification/*metabolism/secondary
MH  - Female
MH  - Humans
MH  - Laminin/metabolism
MH  - Liver Neoplasms/secondary
MH  - Mucins/*metabolism
MH  - Neoplasm Invasiveness
MH  - Ovarian Neoplasms/secondary
MH  - Prognosis
MH  - Receptors, Estrogen/metabolism
MH  - Stomach Neoplasms/*classification/*metabolism/pathology
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
PST - ppublish
SO  - Chin Med Sci J. 1994 Jun;9(2):119-24.