PMID- 8004764
OWN - NLM
STAT- MEDLINE
DCOM- 19940720
LR  - 20190830
IS  - 0165-3806 (Print)
IS  - 0165-3806 (Linking)
VI  - 78
IP  - 1
DP  - 1994 Mar 18
TI  - Differential development of binding sites of two lectins in the vomeronasal axons 
      of the rat accessory olfactory bulb.
PG  - 1-9
AB  - Binding of fluorochrome-conjugated lectins, Bandeiraea simplicifolia lectin-I 
      (BSL-I) and Vicia villosa agglutinin (VVA), to the vomeronasal axons was 
      investigated in the accessory olfactory bulb (AOB) of developing rats at 
      embryonic day (E) 16, 18, and 20, and postnatal day (P) 0, 3, 7, 14, and 28. 
      Intense fluorescence for VVA was first observed at E18, and the position-specific 
      binding pattern observed in adults was established at P0; intense fluorescence 
      for VVA was observed in the posterior 2/3 of the vomeronasal nerve layer (VNL) 
      and glomerular layer (GL) and weak fluorescence was present in the anterior 1/3 
      of these layers. Fluorescence for BSL-I was observed in the posterior half of VNL 
      and GL at P0; the area bound with BSL-I was expanded to the anterior area and 
      intensity of the fluorescence increased as the development proceeded. At P28, 
      binding of BSL-I was observed in the entire VNL and GL as identical to adults. 
      These results indicate that the binding sites of BSL-I and VVA in the vomeronasal 
      axons at the level of rat AOB develop differentially during ontogeny, suggesting 
      that rat VN axons consist of two subpopulations expressing different 
      glycoconjugates.
FAU - Ichikawa, M
AU  - Ichikawa M
AD  - Department of Anatomy and Embryology, Tokyo Metropolitan Institute for 
      Neuroscience, Japan.
FAU - Takami, S
AU  - Takami S
FAU - Osada, T
AU  - Osada T
FAU - Graziadei, P P
AU  - Graziadei PP
LA  - eng
GR  - DC01071-01/DC/NIDCD NIH HHS/United States
GR  - NS20699/NS/NINDS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Brain Res Dev Brain Res
JT  - Brain research. Developmental brain research
JID - 8908639
RN  - 0 (Griffonia simplicifolia lectins)
RN  - 0 (Lectins)
RN  - 0 (Plant Lectins)
RN  - 0 (Receptors, Mitogen)
RN  - 0 (Vicia lectins)
SB  - IM
MH  - Animals
MH  - Axons/*metabolism
MH  - Binding Sites
MH  - Female
MH  - Lectins/metabolism
MH  - Male
MH  - Microscopy, Fluorescence
MH  - Nasal Septum/cytology/*growth & development/innervation
MH  - Olfactory Bulb/cytology/*growth & development/metabolism
MH  - *Plant Lectins
MH  - Pregnancy
MH  - Rats
MH  - Receptors, Mitogen/*metabolism
EDAT- 1994/03/18 00:00
MHDA- 2000/03/23 09:00
CRDT- 1994/03/18 00:00
PHST- 1994/03/18 00:00 [pubmed]
PHST- 2000/03/23 09:00 [medline]
PHST- 1994/03/18 00:00 [entrez]
AID - 0165-3806(94)90002-7 [pii]
AID - 10.1016/0165-3806(94)90002-7 [doi]
PST - ppublish
SO  - Brain Res Dev Brain Res. 1994 Mar 18;78(1):1-9. doi: 
      10.1016/0165-3806(94)90002-7.