PMID- 8012862 OWN - NLM STAT- MEDLINE DCOM- 19940728 LR - 20190830 IS - 0954-7894 (Print) IS - 0954-7894 (Linking) VI - 24 IP - 3 DP - 1994 Mar TI - The importance of appropriate challenges in diagnosing food sensitivity. PG - 291-3 AB - Two patients with clinically significant immunoglobulin E (IgE) mediated reactions to cow's milk which occur only under special circumstances are described. Although double-blind, placebo-controlled food challenges or open food challenges are generally very helpful, certain patients who react only under special circumstances might be missed when these office tests are used. The two reported incidences occurred in older children who seemed to outgrow their cow-milk allergy but still had clinically significant allergic reactions under certain circumstances. FAU - Kaplan, M S AU - Kaplan MS AD - Department of Allergy, Kaiser Permanente Medical Center, Oakland, California 94611-5693. LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Clin Exp Allergy JT - Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology JID - 8906443 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adolescent MH - Animals MH - Child MH - Double-Blind Method MH - Humans MH - Immunoglobulin E/analysis MH - Immunologic Techniques MH - Male MH - Milk/*adverse effects/immunology MH - Milk Hypersensitivity/*diagnosis MH - Skin Tests EDAT- 1994/03/01 00:00 MHDA- 1994/03/01 00:01 CRDT- 1994/03/01 00:00 PHST- 1994/03/01 00:00 [pubmed] PHST- 1994/03/01 00:01 [medline] PHST- 1994/03/01 00:00 [entrez] AID - 10.1111/j.1365-2222.1994.tb00234.x [doi] PST - ppublish SO - Clin Exp Allergy. 1994 Mar;24(3):291-3. doi: 10.1111/j.1365-2222.1994.tb00234.x.