PMID- 8013612
OWN - NLM
STAT- MEDLINE
DCOM- 19940726
LR  - 20190821
IS  - 0903-1936 (Print)
IS  - 0903-1936 (Linking)
VI  - 7
IP  - 3
DP  - 1994 Mar
TI  - Mechanisms and pathology of occupational asthma.
PG  - 544-54
AB  - Since the pathogenesis and the pathological features of occupational asthma are 
      similar to those of nonoccupational asthma, the former represents a very useful 
      model for the investigation of the pathogenesis of asthma in general. More than 
      one mechanism may be operative in occupational asthma. Among the mechanisms 
      proposed, immunological mechanisms and airway inflammation play an important 
      role. There is evidence to confirm that T-lymphocyte activation and local 
      accumulation in the bronchial wall of activated eosinophils occurs in asthma of 
      diverse aetiology, i.e. immunoglobulin E (IgE)-mediated, occupational and 
      intrinsic. Neurogenic pathways should be further investigated as a potential 
      mechanism of modulation and amplification of airway inflammation in occupational 
      asthma.
FAU - Mapp, C E
AU  - Mapp CE
AD  - Institute of Occupational Medicine, University of Padova, Italy.
FAU - Saetta, M
AU  - Saetta M
FAU - Maestrelli, P
AU  - Maestrelli P
FAU - Di Stefano, A
AU  - Di Stefano A
FAU - Chitano, P
AU  - Chitano P
FAU - Boschetto, P
AU  - Boschetto P
FAU - Ciaccia, A
AU  - Ciaccia A
FAU - Fabbri, L M
AU  - Fabbri LM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Eur Respir J
JT  - The European respiratory journal
JID - 8803460
SB  - IM
EIN - Eur Respir J 1995 Apr;8(4):667
MH  - Adult
MH  - *Asthma/etiology/pathology
MH  - Child
MH  - Humans
MH  - Lung/*pathology
MH  - *Occupational Diseases/etiology/pathology
RF  - 114
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
AID - 10.1183/09031936.94.07030544 [doi]
PST - ppublish
SO  - Eur Respir J. 1994 Mar;7(3):544-54. doi: 10.1183/09031936.94.07030544.