PMID- 8019340
OWN - NLM
STAT- MEDLINE
DCOM- 19940729
LR  - 20190920
IS  - 0942-8925 (Print)
IS  - 0942-8925 (Linking)
VI  - 19
IP  - 3
DP  - 1994 May-Jun
TI  - Videofluoroscopy of the pharynx and esophagus in chronic graft-versus-host 
      disease.
PG  - 191-4
AB  - Successful allogeneic bone marrow transplantation (BMT) for hematologic disorders 
      may be complicated by graft-versus-host-disease (GVHD). Chronic GVHD is a 
      systemic disease, involving, among other organs, the skin, mouth, liver, and 
      esophagus. Esophageal involvement results in mucosal inflammation, leading to 
      submucosal fibrosis and, occasionally, formation of webs and strictures. We 
      investigated 25 allogeneic BMT recipients (17 with and eight without chronic 
      GVHD). All patients had a videofluoroscopic study of the pharynx and esophagus to 
      determine the radiographic abnormalities characteristic of chronic GVHD. 
      Oropharyngeal abnormalities (poor bolus control, pharyngeal retention, or 
      excessive mucous secretions) were found in five patients with and three patients 
      without GVHD. Only one patient with GVHD had a pharyngo-esophageal stricture. 
      There was no significant difference between the two groups with regard to 
      pharyngo-esophageal radiographic abnormalities and esophageal symptoms. 
      Radiographic evidence of esophageal motility disorder is not specific for GVHD 
      involvement. In the absence of specific radiographic features, endoscopy is the 
      most accurate method for the diagnosis of esophageal involvement by GVHD.
FAU - Schima, W
AU  - Schima W
AD  - Department of Radiology, University of Vienna, Austria.
FAU - Pokieser, P
AU  - Pokieser P
FAU - Forstinger, C
AU  - Forstinger C
FAU - Uranitsch, K
AU  - Uranitsch K
FAU - Kalhs, P
AU  - Kalhs P
FAU - Schober, E
AU  - Schober E
FAU - Kier, P
AU  - Kier P
FAU - Tscholakoff, D
AU  - Tscholakoff D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Abdom Imaging
JT  - Abdominal imaging
JID - 9303672
SB  - IM
MH  - Adult
MH  - Bone Marrow Transplantation
MH  - Chronic Disease
MH  - Deglutition
MH  - Deglutition Disorders/diagnostic imaging/etiology
MH  - Esophagus/*diagnostic imaging
MH  - Female
MH  - Fluoroscopy
MH  - Graft vs Host Disease/complications/*diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pharynx/*diagnostic imaging
MH  - Video Recording
EDAT- 1994/05/01 00:00
MHDA- 1994/05/01 00:01
CRDT- 1994/05/01 00:00
PHST- 1994/05/01 00:00 [pubmed]
PHST- 1994/05/01 00:01 [medline]
PHST- 1994/05/01 00:00 [entrez]
AID - 10.1007/BF00203504 [doi]
PST - ppublish
SO  - Abdom Imaging. 1994 May-Jun;19(3):191-4. doi: 10.1007/BF00203504.