PMID- 8019959
OWN - NLM
STAT- MEDLINE
DCOM- 19940801
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 74
IP  - 2
DP  - 1994 Jun
TI  - Characterization of a new case of trisomy 8 in acute lymphoblastic leukemia.
PG  - 144-6
AB  - Trisomy 8 is a relatively common finding in acute nonlymphoblastic leukemia 
      (ANLL). In childhood acute lymphoblastic leukemia (ALL) it apparently is much 
      more rare. Although Human Gene Mapping 11 included trisomy 8 as a marker for a 
      subgroup of ALL, morphologic and immunologic characteristics of this entity have 
      not been defined. We describe a case of early T-cell ALL (T-ALL) in a pediatric 
      patient in whom this abnormality was the sole chromosome aberration. In situ 
      hybridization with a chromosome 8-specific alpha-satellite DNA probe was 
      performed. Our data are discussed and compared with pertinent literature.
FAU - Angioni, A
AU  - Angioni A
AD  - Servizio Trasfusionale, Istituto di Ricovero e Cura a Carattere Scientifico, 
      Ospedale Pediatrico Bambino Gesu, Rome, Italy.
FAU - Ruscio, C
AU  - Ruscio C
FAU - Giovannelli, L
AU  - Giovannelli L
FAU - Miano, C
AU  - Miano C
FAU - Rosati, D
AU  - Rosati D
FAU - Balloni, P
AU  - Balloni P
FAU - De Laurenzi, A
AU  - De Laurenzi A
FAU - Mecucci, C
AU  - Mecucci C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Child, Preschool
MH  - *Chromosomes, Human, Pair 8
MH  - Female
MH  - Humans
MH  - Immunophenotyping
MH  - In Situ Hybridization, Fluorescence
MH  - Leukemia-Lymphoma, Adult T-Cell/*genetics
MH  - *Trisomy
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
AID - 0165-4608(94)90013-2 [pii]
AID - 10.1016/0165-4608(94)90013-2 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1994 Jun;74(2):144-6. doi: 10.1016/0165-4608(94)90013-2.