PMID- 8030810
OWN - NLM
STAT- MEDLINE
DCOM- 19940811
LR  - 20161123
IS  - 0003-1348 (Print)
IS  - 0003-1348 (Linking)
VI  - 60
IP  - 8
DP  - 1994 Aug
TI  - The role of intrarectal ultrasound (IRUS) in staging of rectal cancer and 
      detection of extrarectal pathology.
PG  - 571-6; discussion 576-7
AB  - Intrarectal Ultrasound (IRUS) is rapidly becoming an effective tool in the 
      staging of rectal cancer. Twenty-nine consecutive patients with adenocarcinoma of 
      the rectum underwent both CT scanning and IRUS in the preoperative assessment of 
      rectal cancer in an effort to correlate IRUS staging with surgical pathology, 
      correlate tumor staging comparing IRUS with CT scan, and determine incidence of 
      extrarectal pathology by IRUS. Patients were reviewed as to IRUS stage, results 
      of CT scan, TNM stage of extirpated tumor, incidence of genitourinary pathology, 
      and sonographic result of preoperative radiotherapy (RT). The mean age of all 
      patients was 69 years; there were 25 males and four females. Twenty-four patients 
      underwent proctectomy with either low pelvic anastomosis or end stoma; five 
      underwent local surgical therapy. Thirteen patients received preoperative RT. CT 
      scan correlated poorly with IRUS staging of tumors penetrating the muscularis 
      propria. IRUS overstaged 40 per cent, understaged 5 per cent, and correctly 
      staged 55 per cent of patients when compared with pathological specimens. Eleven 
      of the 25 males (44 per cent) had abnormal prostates by IRUS. Five (20%) had 
      further urologic intervention, resulting in two prostatic cancers found. Our data 
      suggests that CT scan staging correlated poorly with IRUS staging. CT poorly 
      determines depth of rectal tumor wall invasion. IRUS correlated well with 
      pathology and understaged 5 per cent of patients before surgery. Genitourinary 
      abnormalities were detected in a significant number of patients. IRUS is an 
      effective modality for preoperative staging of rectal cancer.(ABSTRACT TRUNCATED 
      AT 250 WORDS)
FAU - Harnsberger, J R
AU  - Harnsberger JR
AD  - Department of Surgery, St. Louis University School of Medicine, Missouri.
FAU - Charvat, P
AU  - Charvat P
FAU - Longo, W E
AU  - Longo WE
FAU - Vernava, A M 3rd
AU  - Vernava AM 3rd
FAU - Salimi, Z
AU  - Salimi Z
FAU - Arends, T
AU  - Arends T
FAU - Daniel, G
AU  - Daniel G
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am Surg
JT  - The American surgeon
JID - 0370522
SB  - IM
MH  - Adenocarcinoma/*diagnostic imaging/pathology/surgery
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Combined Modality Therapy
MH  - Female
MH  - Humans
MH  - Intestinal Mucosa/diagnostic imaging/pathology
MH  - Lymphatic Metastasis
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Invasiveness
MH  - Neoplasm Staging
MH  - Prospective Studies
MH  - Prostate/diagnostic imaging
MH  - Prostatic Neoplasms/diagnostic imaging
MH  - Rectal Neoplasms/*diagnostic imaging/pathology/surgery
MH  - Rectum/surgery
MH  - Sensitivity and Specificity
MH  - Tomography, X-Ray Computed
MH  - Ultrasonography
EDAT- 1994/08/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1994/08/01 00:00
PHST- 1994/08/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1994/08/01 00:00 [entrez]
PST - ppublish
SO  - Am Surg. 1994 Aug;60(8):571-6; discussion 576-7.