PMID- 8034781
OWN - NLM
STAT- MEDLINE
DCOM- 19940816
LR  - 20190830
IS  - 0303-6979 (Print)
IS  - 0303-6979 (Linking)
VI  - 21
IP  - 5
DP  - 1994 May
TI  - Influence of a single application of subgingival chlorhexidine gel or 
      tetracycline paste on the clinical parameters of adult periodontitis patients.
PG  - 351-5
AB  - The clinical effects of subgingivally placed 1% chlorhexidine gel (w/w) and 40% 
      tetracycline (w/w) paste in periodontal pockets of 22 adult periodontitis 
      patients were studied. The 2 agents were applied following scaling and root 
      planing in pockets exceeding 4 mm. The patients were randomly divided into 3 
      groups: (a) scaling and root planing (SCRP) only, the control group; (b) corsodyl 
      gel+SCRP; (c) Tetracycline paste+SCRP. Gel or paste were gently applied using a 
      syringe with a blunt needle until the selected pocket was overfilled. Evaluations 
      were made of clinical parameters including the plaque index (PI), gingival index 
      (GI), bleeding index (GI-S), probing pocket depths, probing attachment levels and 
      position of the gingival margin. The results suggested that all the treatment 
      modalities were effective in producing statistically significant improvements in 
      clinical parameters. It was concluded that the conventional treatment modalities 
      were essential in the treatment of periodontal diseases, but in view of the 
      structure of the periodontal pocket and adjacent complex root surface, 
      subgingival drug application in certain cases, might also provide adjunctive 
      improvement.
FAU - Unsal, E
AU  - Unsal E
AD  - Department of Periodontology, Ankara University, Faculty of Dentistry, Turkey.
FAU - Akkaya, M
AU  - Akkaya M
FAU - Walsh, T F
AU  - Walsh TF
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Clin Periodontol
JT  - Journal of clinical periodontology
JID - 0425123
RN  - F8VB5M810T (Tetracycline)
RN  - MOR84MUD8E (chlorhexidine gluconate)
RN  - R4KO0DY52L (Chlorhexidine)
SB  - IM
MH  - Administration, Topical
MH  - Adult
MH  - Analysis of Variance
MH  - Chlorhexidine/administration & dosage/*analogs & derivatives
MH  - Dental Plaque Index
MH  - Dental Scaling
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Periodontal Index
MH  - Periodontal Pocket/*drug therapy
MH  - Periodontitis/*drug therapy
MH  - Root Planing
MH  - Tetracycline/*administration & dosage
EDAT- 1994/05/01 00:00
MHDA- 1994/05/01 00:01
CRDT- 1994/05/01 00:00
PHST- 1994/05/01 00:00 [pubmed]
PHST- 1994/05/01 00:01 [medline]
PHST- 1994/05/01 00:00 [entrez]
AID - 10.1111/j.1600-051x.1994.tb00725.x [doi]
PST - ppublish
SO  - J Clin Periodontol. 1994 May;21(5):351-5. doi: 
      10.1111/j.1600-051x.1994.tb00725.x.