PMID- 8037335
OWN - NLM
STAT- MEDLINE
DCOM- 19940818
LR  - 20161123
IS  - 0192-8562 (Print)
IS  - 0192-8562 (Linking)
VI  - 16
IP  - 3
DP  - 1994 Aug
TI  - Current controversy: is computed tomography scan of the chest needed in patients 
      with Wilms' tumor?
PG  - 191-3
AB  - PURPOSE: Reports from the National Wilms' Tumor Study (NWTS) Group on the subject 
      of chest computed tomography (CT) versus chest radiograph for the detection of 
      lung metastases from Wilms tumor are reviewed. PATIENTS AND METHODS: Thirty-two 
      patients with lung nodules detected by CT, with negative chest radiographs, were 
      identified. Five patients were excluded from further analysis. Of the remaining 
      27 patients, 18 were treated as stage IV, receiving therapy with three drugs and 
      lung irradiation; the other nine were treated with less intensive therapy and no 
      lung irradiation. The investigators found no significant difference between the 
      overall survival between these two groups of patients (94% and 88%, 
      respectively). In an earlier study, four of 11 children (36%) with normal chest 
      radiographs and positive chest CT results were treated by ignoring the CT 
      findings. These data compared with a relapse rate of only 20% in a control 
      population. RESULTS: The studies do not statistically address the question of the 
      impact of CT of the chest on survival. CONCLUSIONS: All children should have the 
      benefit of the most sensitive imaging available, including CT, to detect tumor 
      spread.
FAU - Cohen, M D
AU  - Cohen MD
AD  - Department of Radiology, Riley Hospital for Children, Indiana University Medical 
      Center, Indianapolis 46202-5200.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Pediatr Hematol Oncol
JT  - The American journal of pediatric hematology/oncology
JID - 7908071
SB  - IM
MH  - Humans
MH  - Kidney Neoplasms/*diagnostic imaging
MH  - *Radiography, Thoracic
MH  - *Tomography, X-Ray Computed
MH  - Wilms Tumor/*diagnostic imaging
EDAT- 1994/08/01 00:00
MHDA- 1994/08/01 00:01
CRDT- 1994/08/01 00:00
PHST- 1994/08/01 00:00 [pubmed]
PHST- 1994/08/01 00:01 [medline]
PHST- 1994/08/01 00:00 [entrez]
PST - ppublish
SO  - Am J Pediatr Hematol Oncol. 1994 Aug;16(3):191-3.