PMID- 8056994 OWN - NLM STAT- MEDLINE DCOM- 19940915 LR - 20131121 IS - 0268-1315 (Print) IS - 0268-1315 (Linking) VI - 9 IP - 2 DP - 1994 Summer TI - Isoniazid and antidepressants: is there cause for concern? PG - 123-5 AB - The antituberculous drug isoniazid has weak monoamine oxidase inhibiting properties. Drug and dietary restrictions generally applied to the use of monoamine oxidase inhibitors (MAOI) have not been routinely recommended with its use. Here we report three cases in which antidepressant drugs and isoniazid were co-administered. In two, adverse events, possibly due to an interaction between the drugs prescribed are described. We suggest that the combination of isoniazid and antidepressants be used with caution until further data are accumulated. FAU - Judd, F K AU - Judd FK AD - Fairfield Infectious Diseases Hospital, Australia. FAU - Mijch, A M AU - Mijch AM FAU - Cockram, A AU - Cockram A FAU - Norman, T R AU - Norman TR LA - eng PT - Case Reports PT - Journal Article PL - England TA - Int Clin Psychopharmacol JT - International clinical psychopharmacology JID - 8609061 RN - 0 (Antidepressive Agents) RN - V83O1VOZ8L (Isoniazid) SB - IM MH - Adult MH - Antidepressive Agents/*adverse effects MH - Drug Interactions MH - Drug Therapy, Combination MH - Humans MH - Isoniazid/*adverse effects MH - Male EDAT- 1994/01/01 00:00 MHDA- 1994/01/01 00:01 CRDT- 1994/01/01 00:00 PHST- 1994/01/01 00:00 [pubmed] PHST- 1994/01/01 00:01 [medline] PHST- 1994/01/01 00:00 [entrez] PST - ppublish SO - Int Clin Psychopharmacol. 1994 Summer;9(2):123-5.